Dear R-users (and developers),

I am looking for an efficient framework to carry out parameter estimations based on MCMC (optionally with specified priors). My goal is as follow: * take ANY R-function returning a likelihood-value (this function may itself call external programmes or other code!) * run a sampler that covers the multidimensional parameter space (thus creating a posterior distribution)
* do the above efficiently (!)

What I want to estimate with this type of setup (apart from the optimal parameter values themselves): * parameter uncertainty (i.e. the posterior distribution, indicating how much support the data give to each model parameter)
* parameter interdependency (to somehow measure effective model complexity)
Both I would extract from the MCMC-trace.

Sounds simple? It possibly is - just not for me.
I compared several MCMC algorithms implemented in R, from Win/OpenBUGS over MCMCmetrop1R (MCMCpack; my current favourite) and metrop (mcmc) to gibbs and rwmetrop (LearnBayes) and gibbs_met (gibbs.met). These implementations differ dramatically in efficiency (MCMCmetrop1R was over 20 times faster than gibbs_met). Since my functions can be complex (mainly ODEs, complex environmental models programmed in Fortran or C to be called by the system-function), I cannot use OpenBUGS or JAGS.

MCMCmetrop1R samples from a multinormal distribution, but I would like to have the option to use priors (that's what I refer to as "Bayesian" here: sorry for irritating statisticians with this interpretation). HOW?

What I did so far (in vain) to find the answer:
I searched the R-help list (MCMC, Bayes) for suitable threads.
I looked at all packages listed in R task view Bayesian (http://cran.r-project.org/web/views/Bayesian.html), even those written for specific problems (e.g. regression) I searched "the internet" for alternative names for the concepts, or alternative implementation frameworks (e.g. sage)

Before I start programming (in C inefficiently myself), I would like to seek your advice.

Any help (also implementations in other languages/software as long at it is GPL or alike) would be appreciated!

Cheers,

Carsten

--
Dr. Carsten F. Dormann
Department of Computational Landscape Ecology
Helmholtz Centre for Environmental Research-UFZ Permoserstr. 15
04318 Leipzig
Germany

Tel: ++49(0)341 2351946
Fax: ++49(0)341 2351939
Email: carsten.dorm...@ufz.de
internet: http://www.ufz.de/index.php?de=4205

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