MES or HEPES, I reckon.
Both of them can lose definition for the electron density in the
morpolino/piperazine 6-membered ring due to flexibility between the ring and
the sulphonic acid group when - leading to the tadpole-like density you
describe.
HTH,
Dave
--
Dr David C. Briggs CSci
A MES buffer molecule ?
> Le 13 mars 2022 à 18:08, doriano lamba a écrit :
>
> Glycerol-3-phosphate?
> My 2cents
> DL
> Il 2022-03-13 15:19 Amir Khan ha scritto:
>> Hi,
>> I wonder whether anyone can advise on the ‘tadpole’ like density.
>> The head is currently a phosphate
>> and I’ve placed a
On 13/03/2022 14:05, Tomas Malinauskas wrote:
Dear All,
Is it possible to add hydrogens to a specific residue using Coot?
Something like Calculate -> Scripting -> Python -> coot_reduce(0) but
targeting one residue only.
sprout_hydrogens(0, "L", 101, "") # or some such: molecule-number
Dear All,
Is it possible to add hydrogens to a specific residue using Coot?
Something like Calculate -> Scripting -> Python -> coot_reduce(0) but
targeting one residue only.
I thank you for your help.
Best wishes,
Tomas
