Dear Klaus,
We've had a lot of luck with ethylene glycol and isopropanol, using them
successfully in cases where DMSO affects diffraction.
Best wishes
Richard
=
Dr Richard Bayliss, Reader in Structural Biology
Department of Biochemistry
Henry Wellcome Building
Does anyone know how to access the 'Measure Cell' function in iMosflm? This
function in ipmosflm allowed you to click on a pair of spots, then input the
number of diffraction orders, to output a rough measure of the cell length.
Any help appreciated!
Thanks
Richard
Two MRC-funded PhD studentships are available in the laboratory of Richard
Bayliss at the University of Leicester starting in October 2013. The Department
of Biochemistry provides an outstanding environment in research training in
structural biology and structure-based drug design and
Dear Wenhe,
One example we have is the protein kinase Nek2. We co-crystallised with ADP and
then soaked in the inhibitors. The activation loop was free to move around and
adopt a number of different conformations (e.g. to DFG-out conformation).
References:
Westwood I, Cheary D-M, Baxter JE,
A position is available in the Centre for Translational Therapeutics (CTT)
within the College of Medicine, Biological Sciences and Psychology for a
talented postdoctoral structural biologist to work on a collaborative in-house
structural biology projects, with an emphasis on structure-based
A position is available in the Department of Biochemistry for a talented
postdoctoral structural biologist to work on a new 3 year collaborative project
with MRC Technology focussed on protein structure-based drug discovery and
development. The scientist will work in the groups of Prof. Mark
We are looking for an ambitious and highly-motivated postdoctoral research
associate who has expertise in protein crystallography to join the team of Dr
Richard Bayliss within the Department of Biochemistry. The position is funded
by a 5-year Cancer Research UK Programme Grant, which provides a
A postdoctoral research post is available to undertake translational structural
biology work on a kinase target within my research group in the Department of
Biochemistry. My group is located in the state-of-the-art Henry Wellcome
Building with access to excellent facilities for biochemical
