Re: [ccp4bb] definition of "apo" and alternatives?

2018-02-01 Thread Roman Fedorov
Dear Colleagues, I wish to apologise for any offence that may have been caused by the inappropriate content of the email from Johannes Cramer, which does not represent the views of the rest of our research group. With kind regards, Roman Fedorov

Re: [ccp4bb] definition of "apo" and alternatives?

2018-01-31 Thread Bernhard Rupp
or cofactor. I think it depends to a degree on context and history of the field… Best, BR From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Johannes Cramer Sent: Wednesday, January 31, 2018 6:34 AM To: CCP4BB@JISCMAIL.AC.UK Subject: [ccp4bb] definition of &quo

Re: [ccp4bb] definition of "apo" and alternatives?

2018-01-31 Thread Stefano Trapani
See also the IUPAC reccomandations : https://goldbook.iupac.org/html/A/A00417.html https://goldbook.iupac.org/html/H/H02836.html --- Stefano Trapani Maître de Conférences http://www.cbs.cnrs.fr/index.php/fr/personnel?PERS=Stefano%20Trapani - Centre de

Re: [ccp4bb] definition of "apo" and alternatives?

2018-01-31 Thread F.Xavier Gomis-Rüth
Hi Johannes, this is normal textbook knowledge, which got perverted over time and misusage. Just check with a serious dictionary like Merrian Webster or even the Wikipedia (see below). Best regards, Xavier https://www.merriam-webster.com/dictionary/apoenzyme

[ccp4bb] definition of "apo" and alternatives?

2018-01-31 Thread Johannes Cramer
Dear collegues, a while ago, there was a discussion in the board on the term apo-structure as a way to descibe a native, free, or unbound protein (no ligands). I think the conclusion was that an apo-form is a halo enzyme lacking a cofactor and should not be used as a substitute for "unbound". We