-Caveat Lector-

 >From Eurekalert!,
http://www.eurekalert.org/releases/pu-bpm062001.html

Contact: Emil Venere
[EMAIL PROTECTED]
765-494-4709
Purdue University

Biotechnology promises major advances for U.S. Army

WEST LAFAYETTE, Ind. - A report being released today (Wednesday, 6/20)
recommends that the U.S. Army take advantage of dramatic advancements in
biotechnology that promise to help soldiers survive and perform better in
the 21st century.

The report, from the National Research Council's Board on Army Science and
Technology, was prepared by a 16-member committee chaired by Michael
Ladisch, a distinguished professor of biomedical engineering and
agricultural and biological engineering at Purdue University. The council is
the principal operating arm of the National Academy of Sciences, the
National Academy of Engineering and the Institute of Medicine.

By the year 2025, biotechnology will likely bring advances such as "rugged
computer memories" made from genetically engineered proteins, camouflage
materials and lightweight armor inspired by living organisms, portable
solar-power systems, "biological markers" that help to distinguish friendly
soldiers from the enemy, wristwatch-size sensors and devices that detect
biological and chemical warfare agents. Research also promises to make
possible the creation of new vaccines, drugs and wound-healing technologies,
and medical applications that provide broad benefits to world health, states
the report.

"These are but a few of a myriad of possibilities, some of which may never
be developed for lack of commercial incentive, thus challenging the Army to
devise ways of influencing their development," according to the report,
"Opportunities in Biotechnology for Future Army Applications."

Recommendations in the report stress the importance of developing defensive
technologies aimed at improving the survivability and effectiveness of U.S.
soldiers. The report specifically does not address the use of biotechnology
for offensive applications.

To illustrate the dramatic significance of emerging technologies, the report
includes hypothetical, but realistic, battlefield scenarios in the year
2025.

"Although soldiers in 2025 may look much the same as their present-day
counterparts, they will be drawn from a society that has been armed by
biotechnology with increased strength and endurance and superior resistance
to disease and aging," the report states. "By then, biosensors may be able
to detect chemical, biological and environmental threats of all kinds,
bio-electronics components could enable combat systems to survive in
high-radiation environments, biologically inspired materials could provide
light protective armor for soldiers, and therapies for shock trauma from
excessive bleeding could be developed."

Biotechnology uses organisms, tissues, cells or the molecular components
derived from living things to make products or to perform functions. It's a
technology used to produce drugs and antibiotics like penicillin, and to
make new materials and devices. Biotechnology also sometimes involves
altering the workings of cells or components inside cells, including their
genetic material.

Ladisch said the committee, made up of experts from industry, academia and
government, was formed in late 1999 to create the report, which also was
reviewed by an independent group of researchers before it was approved.

"Some of these ideas may really seem far out because we are looking toward
the year 2025," Ladisch said.

The report includes insights about likely advances resulting from research
into the genetic structure and function of humans and other organisms,
including possible biological warfare agents.

"If soldiers on the battlefield are exposed to a biowarfare agent, advances
in genomics could make it possible to quickly identify this agent and
produce a vaccine," Ladisch said.

The report has two overall conclusions:

* To keep pace with the unprecedented rate of discovery and the anticipated
increase in biotechnology developments, the Army will have to establish new,
effective partnerships with the emerging biotechnology industry, participate
in research and develop the capabilities to act on opportunities as they
arise.

* Because commercial markets for medical applications will drive many
advances in biotechnology, Army scientists and engineers must expand their
understanding of biology's role in research leading to military
applications.

The report recommends that the Army adopt new approaches to work with the
private sector, encouraging relationships between government and industry.
The report also urges the Army to invest in education, assembling "a cadre
of science and technology professionals capable of translating advances in
the biosciences into engineering practice." Also, to help speed the
development of certain technologies, the report suggests that the Army focus
its research in several high-priority areas, including:

* New types of rugged, high-capacity computer memories based on proteins to
store data in portable battlefield computers carried by individual soldiers.

* "Self-replicating" wound-healing technologies, such as methods for growing
new skin for burn victims, growing blood vessels and regenerating bones for
the wounded.

* Technologies aimed at making new vaccines in the battlefield to treat
exotic diseases and to counter biological warfare agents.

* Developing new drugs and therapies to treat shock.

* Using the genetic characteristics of soldiers to increase the
effectiveness of vaccines. The report notes that Army-sponsored research
benefits society as a whole and has historically promoted the development of
drugs to fight diseases, such as malaria, prevalent in the world's poorest
regions.

"By 2020, an estimated 7 billion to 8 billion people will live in less
affluent areas of the world," states the report. "Because it must be
prepared to deploy forces in these areas, the Army should continue to remain
closely involved in the development of therapeutics that could not only
protect U.S. forces, but also contribute to world health."

###
NOTE TO JOURNALISTS: Copies of the report are available from the National
Academy of Sciences by contacting Jennifer Wenger or Christian Dobbins,
202-334-2138; [EMAIL PROTECTED]

Sources: Michael Ladisch, 765-494-7022, [EMAIL PROTECTED]
Jennifer Wenger, 202-334-2138, [EMAIL PROTECTED]

Copies of the report are available from the National Academy Press for
$27.75 (prepaid) plus shipping charges of $4.50 for the first copy and 95
cents for each additional copy; call 202-334-3313 or 800- 624-6242, or order
on the Internet at http://www.nap.edu.

Writer: Emil Venere, 765-494-4709, [EMAIL PROTECTED]

Other source: Christian Dobbins, 202-334-2138; [EMAIL PROTECTED]

Related Web sites:
Michael Ladisch: http://www.ecn.purdue.edu/BME/People/Faculty/ladisch
National Academy Press: http://www.nap.edu

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