On Mon, Jun 15, 2009 at 3:21 PM, Arnon Lavie <la...@uic.edu> wrote: > we collected SAD data sets to 3.0 A on our protein, once as a Se-Met > protein and once soaked with a mercury compound. Data statistics indicate an > anomalous signal in both data sets. However, the maps are not great. Is it > possible to combine the phase information from the two data sets? We have > been using Solve/Resolve for the individual SAD data sets. If any of you > know of a solve script (or an alternative program) that would combine the > two, please reply.
phenix.autosol can do this - I haven't tried this myself, but it will definitely support multiple datasets (including combinations of methods, e.g. SAD + MIR). By default, it will use Phaser for SAD, but you can also use SOLVE. (It also runs RESOLVE automatically.) I believe SHARP will also handle multiple datasets easily, but it's been a while since I've used it. -Nat
