POSTDOCTORAL POSITION IN STRUCTURAL BIOLOGY WASHINGTON UNIVERSITY SCHOOL OF MEDICINE, ST. LOUIS MO
An NIH-funded Postdoctoral position is immediately available to study the structure and function of proteins involved in obstructive pulmonary diseases (asthma and COPD). These proteins represent key therapeutic targets for the treatment of asthma and COPD. This work will be done in collaboration with individuals in the Pulmonary Division. Our lab is located in the Department of Internal Medicine (Pulmonary Division) and has state-of-the-art equipment for protein expression and purification as well as direct access to crystallization robotics in addition to instrumentation for protein characterization (CD, MALS, AUC) and probing protein-protein interactions (ITC, SPR). Instrumentation for in-house X-ray data collection is available, and we have frequent access to synchrotron sites (either directly or via remote data collection). Excellent computation facilities are available. Enthusiastic and self-motivated individuals with (or expecting) a PhD in Biochemistry or a related discipline are encouraged to apply. The ideal candidate will have extensive experience in all aspects of protein expression, purification, characterization and crystallization. Experience in X-ray crystallography and the use of biophysical methods to characterize protein-protein interactions as well as cell-binding assays would be advantageous but not required as training can be provided. Must have a strong interest in the biology of human diseases. This is an excellent position for a structural biologist wanting to learn more about chronic inflammatory diseases or (vice versa) an individual with experience in inflammatory disease research wanting to learn structural biology. Excellent oral and written communication skills are required. Interested candidates are encouraged to apply or inquire by submitting (via email) a curriculum vitae (including a summary of research experience and interests, and contact information for 2-3 references) to Tom J. Brett: tbr...@wustl.edu http://brettlab.dom.wustl.edu/ Contact Info: Tom J. Brett, PhD Assistant Professor of Medicine Division of Pulmonary and Critical Care Washington University School of Medicine Campus Box 8052, 660 S. Euclid Saint Louis, MO 63110
