-----BEGIN PGP SIGNED MESSAGE----- Hash: SHA1 Hi,
in my opinion the resolution limit of crystals from large complexes/ membrane proteins is more likely due to lattice imperfections and long-range disorder, and cold neither cold temperatures nor stronger radiation sources would circumvent this problem. Tim On 01/09/2012 08:02 PM, Cale Dakwar wrote: > In theory, no: sub-angstrom resolution can be obtained for any and all > proteins, including membrane proteins, and for large complexes. In > reality, it becomes technically very difficult to achieve; you would need > ever-colder temperatures and ever-stronger irradiation sources. > > P.S. In theory, the only limit to describing the location of the atoms > would be described by the heisenberg uncertainty principle. > > > > On Mon, Jan 9, 2012 at 1:15 PM, Theresa H. Hsu <theresah...@live.com> wrote: > >> Dear crystallographers >> >> A theoretical question - can sub-angstrom resolution structures only be >> obtained for a limited set of proteins? Is it impossible to achieve for >> membrane proteins and large complexes? >> >> Theresa >> > - -- - -- Dr Tim Gruene Institut fuer anorganische Chemie Tammannstr. 4 D-37077 Goettingen GPG Key ID = A46BEE1A -----BEGIN PGP SIGNATURE----- Version: GnuPG v1.4.10 (GNU/Linux) Comment: Using GnuPG with Mozilla - http://enigmail.mozdev.org/ iD8DBQFPCz+YUxlJ7aRr7hoRAro2AKD502CdF5N3AK2Bb38hxhAey0nQagCg/GSB gONh31woZI+cxJqEhSVZHjM= =4B4D -----END PGP SIGNATURE-----
