-Caveat Lector-

Controversial lead paint study comes under fire

The Associated Press

BALTIMORE (August 23, 2001 9:57 p.m. EDT) - The government is
investigating a lead-paint study of poor city children that a judge has
compared to Nazi typhus experiments on concentration camp prisoners.

The probe is being conducted by the Health and Human Services
Department's Office for Human Research, which briefly shut down human
research at Johns Hopkins University this year following the death of an
asthma study volunteer.

Investigators are looking into a federally funded study by the Kennedy Krieger
Institute, which is also affiliated with Johns Hopkins, that examined
inexpensive alternatives for removing lead paint.

Landlords were paid to recruit about 100 families with healthy children to live
in their homes during the early 1990s. Children - who can develop brain
damage if they eat lead paint chips - were to be tested periodically to see
how well the abatement methods worked.

Lawsuits have been filed on behalf of two children who allegedly suffered
elevated blood-lead levels and irreversible brain damage in the study. The
suits seek unspecified damages from the landlords and Kennedy Krieger, a
children's hospital and research center.

Last week, state Judge Dale R. Cathell allowed the lawsuits to proceed and
criticized the university's Institutional Review Board for protecting the
interests of researchers at the expense of the children.

The judge said the research project contained problems similar to those in
the Tuskegee Syphilis Study, which was conducted on uneducated black
men in Alabama from the 1930s to 1970s. Cathell also drew comparisons to
typhus experiments conducted on prisoners at the Buchenwald concentration
camp during World War II.

Kennedy Krieger chief executive Gary Goldstein has said the children ran a
high risk of lead paint exposure because they already lived in older houses.

In the asthma study case, federal regulators found that researchers had
bypassed several safety checkpoints.


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