I also agree that you should start with you are familiar with.

In my personal experience, after experimenting some. I choose the
Basic Amazon AMI, which is Centos compatible. It was what worked best
for me.

[]s

On Nov 13, 4:56 pm, ydjango <neerash...@gmail.com> wrote:
> I am setting up nginex, apache, python django, mysql based application
> on EC2. I expect high web traffic and high mysql query usage. Mysql
> and web server will on seperate servers.
>
> Which linux distro should I use for heavy production use - Ubuntu,
> Centos or Debian?
>
> Does it matter?
>
> I see most instructions on web is using Ubuntu and it seems it is
> considered easiest to set up. But I read somewhere that Ubuntu is not
> for server use. What is the downside if I chose ubuntu?

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