Thank you very much for your answer.

Are 10 000 iterations also used when I am running a Monte Carlo simulation
in qdec?

Thanks, Marie

2012/6/9 Douglas N Greve <gr...@nmr.mgh.harvard.edu>

> they are two different correction schemes. If they gave the same answer,
> then it would not make sense to have both. the monte carlo tries to
> compute the probability of a cluster of the given size under the null
> hypothesis. FDR controls for the number of false positives relative to
> the total number of positives under the assumption that if any 5% of
> your positives are false, then you would not change your conclusion.
>
> For monte carlo, we generally use 10000 iterations. If you are using the
> whole hemisphere, then you can used the cached tables. See the
> "command-line" tutorial.
>
> doug
>
> On 06/08/2012 08:03 AM, Marie Schneider wrote:
> > Dear FreeSurfer experts,
> >
> > I have some questions about corrections for multiple comparisons in
> > FreeSurfer. I have two samples, one consisting of two groups and one
> > consisting of three groups.
> >
> > I do the comparison with the sample of two groups in qdec. Correcting
> > for multiple comparisons, I get a significant result using FDR, but no
> > significant result using Monte Carlo simulation. How can that be?
> >
> > I analyze the sample with the three groups by mri_glmfit. In your
> > tutorial, I only found how to correct for multiple comparisons with
> > the Monte Carlo simulation using the command line, but not how to
> > correct with FDR using the command line. Is there a possibility to do
> > this? If not, how many iterations are usual to use within the Monte
> > Carlo simulation?
> >
> > Any help is appreciated.
> >
> > Thank you very much,
> >
> > Marie
> >
> >
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>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
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>
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