In spite of the apparent advantage, FS are so uniquely demanding while 
sectioning, that the manual "touch" could never be substituted by an automatic 
feeding mechanism.
Buy a good manual cryostat. I always used Leica. Ask for a demo.
René J.

From: Ed Roy <e...@illinois.edu>
To: histonet@lists.utsouthwestern.edu
Sent: Friday, May 13, 2011 5:55 PM
Subject: [Histonet] motorized cryostat

I have a small research lab with an old (very old) Minot IEC microtome 
cryostat, which is on its last legs. In starting to shop for a new one, I was 
wondering how much difference a motorized one would make.  We do mostly fresh 
frozen (unfixed) mouse brain and lymph node sections. Are the sections any 
better?
Thanks for any opinions on this and any recommendations on a good cryostat at a 
reasonable cost.

Ed Roy

-- 
Edward Roy, PhD
Professor of Pathology
Professor of Molecular and Integrative Physiology
University of Illinois at Urbana-Champaign
506 S. Mathews Ave.
Urbana, IL 61801
217 333-3375


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