Why would you like to avoid detection of intracellular Abeta inclusions? //Daniel
On Wed, Oct 26, 2011 at 8:51 AM, Hobbs, Carl <carl.ho...@kcl.ac.uk> wrote: > > Be careful: HIER may expose not only extracellular amyloid plaques but also > intracellular APP ( or...is it intracellular A beta ???? ;-)) > Eg: with 6E10.... it is directed against an epitope found in APP and also > A beta: if you do Formic acid, only extracellular plaques are > positive...after HIER, there is also intracellular positivity. > In my experience. > Some examples of this can be found here, in the image gallery : > http://www.immunoportal.com/ > > > Whichever way you go....good luck. > > Carl > > > Carl Hobbs > Histology Manager > Wolfson CARD > School of Biomedical Sciences > Kings College London > Guys Campus > SE1 1UL > Tel: 020 78486813 > Fax: 020 78486816 > 020 78486813 > > _______________________________________________ > Histonet mailing list > Histonet@lists.utsouthwestern.edu > http://lists.utsouthwestern.edu/mailman/listinfo/histonet > _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet