Like all other things 'histology', blade choice depends on so many different 
things!  Tissue type, fixation, paraffin type, mircrotome and associated blade 
holder, humidity in the workroom, etc.  I know there are people who will 
poo-poo this opinion--so try it for yourself!
 
Contact your vendors and ask for samples of every blade you think you'll like.  
They'll send samples from 2 blades to a 10-blade mini pack.  Then sit down and 
TRY them.  You WILL have one blade work significantly better than the 
others--you may also want a second type for hard or decal tissues.  
 
If you're concerned about cost, also consider the extra time your techs need to 
produce a GOOD slide on an blade that isn't optimal for your lab.  Tech time 
trumps blade cost every time. One 'cut thru' block could cost your patient a 
correct diagnosis and the lab a chunk to make it right.
 
Most techs have a favorite, but most techs also don't care what blade they use 
as long as they don't have to struggle to produce good work.  Nothing worse 
than facing a tiny pediatric kidney core knowing you have to produce 15+ slides 
on a crappy blade.  My antiperspirant isn't up to that task!!
 
Cheryl

Cheryl Kerry, HT(ASCP) 
Full Staff Inc. 
Staffing the AP Lab by helping one GREAT Tech at a time.  
281.852.9457 Office
800.756.3309 Phone & Fax 
ad...@fullstaff.org 

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