Good Morning,
We are beginning to optimize and validate the four antibodies for colon
MMR (MLH1, MSH2, MSH6, PMS2).
We are having difficulties gathering cases to show appropriate loss of
staining for all four antibodies.  Can anyone share ideas on how this
can be accomplished?  We are already reaching out to our genetics
department and reference lab for cases we have sent in the past.

Thank you :-)

Melissa Kuhnla 
Lead Medical Technologist for IHC and FISH
Catholic Health Services of Long Island
Regional Laboratory Services



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