For large specimens you need a "horizontal" or sledge microtome. Leitz (Leica) 
manufactures the best, but you could try an OMS from Reichert although I am not 
sure they stll are manufactured because Leica swallowed Reichert some years 
ago.Another alternative, and probably even better than the Leitz (Leica), is a 
Spencer (American Optical) sliding microtome Model 860 For me this is the best 
all-around ever manufactured sliding microtome and not too long ago a saw one 
for sale in e-Bay. Why don't you try looking for it. It will be much cheaper 
than any modern horizontal microtome and far better than any new one.René J. 


     On Wednesday, October 7, 2015 9:08 AM, "Goetz, Freya E. via Histonet" 
<histonet@lists.utsouthwestern.edu> wrote:
   

 Good morning!
I was wondering if anyone has microtome opinions they would like to share. We 
have an ultramicrotome but I am looking for a microtome that could cut larger 
pieces of tissue embedded in plastic. I am hesitant to go with Leica because 
service is so expensive but I’m looking for honest opinions.

Thanks and have a nice day!

Freya
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