I have a validation file for ER, PR, and HER2 IHC testing on decalcified bone specimens with metastatic breast cancer. I compared the results with other specimens from the same patient (usually the primary breast cancer) that were not decalcified.
Richard Richard W. Cartun, MS, PhD Director, Histology & The Martin M. Berman, MD Immunopathology & Morphologic Proteomics Laboratory Director, Biospecimen Collection Programs Assistant Director, Anatomic Pathology Hartford Hospital 80 Seymour Street Hartford, CT 06102 (860) 972-1596 (860) 545-2204 Fax -----Original Message----- From: Teri Johnson via Histonet [mailto:histonet@lists.utsouthwestern.edu] Sent: Tuesday, April 05, 2016 2:50 PM To: 'histonet@lists.utsouthwestern.edu' Subject: [Histonet] Validating IHC on decalcified specimens Hi Histonetters, Can someone tell me if they do anything specific to validate their IHC markers on decalcified specimens? If no, do you test them anyway? Teri Johnson Manager, Clinical Trial Testing Genoptix, Inc., a Novartis company BioPharma 1811 Aston Avenue Carlsbad, CA 92008 USA Phone +1 760 516 5954 tejohn...@genoptix.com<mailto:tejohn...@genoptix.com> www.genoptix.com<http://www.genoptix.com/> ________________________________ CONFIDENTIALITY NOTICE: This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and contains information that is confidential and proprietary to Genoptix Medical Laboratory or its subsidiaries. Any unauthorized review, use, disclosure or distribution is prohibited. If you are not the intended recipient, immediately contact the sender by e-mail and destroy all copies of the original message. _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet This e-mail message, including any attachments, is for the sole use of the intended recipient(s) and may contain confidential and privileged information. Any unauthorized review, use, disclosure, or distribution is prohibited. If you are not the intended recipient, or an employee or agent responsible for delivering the message to the intended recipient, please contact the sender by reply e-mail and destroy all copies of the original message, including any attachments. _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet