In my experience, rushing to process fatty or inadequately fixed specimens is a 
fool's game.
In my opinion, this problem cannot be solved by the histotechs- it begins with 
the grossers and is one for the pathologists to solve at the grossing bench.  

Suggestion #1 Do nothing and let the medical director pathologist/ sign it 
out/deal w this individual case.

Suggestion #2  Sometimes a decent section can be obtained after changing 
paraffin. 
[place the blocks in molds and melt the blocks and change to new paraffin- let 
them sit in the embedding center in the new paraffin for 60 minutes. Re-embed 
in new paraffin (2 changes) and then re-embed.]

Suggestion #3 Reprocess these blocks if permitted, recognizing that breast 
markers (if cancerous) may be erroneous.

Suggestion #4 Seek to prevent future occurrences by adjusting behavior at the 
grossing bench.
a) first ensuring adequate fixation and b) second ensuring adequate length/time 
of processing.  


Steve A. McClain, MD
631 361 4000

What is the best way to handle Breast specimens that were grossed too thick and 
did not process well?  Our medical director does not want us to reprocess the 
tissue but it is almost impossible to get even a remotely decent section. If 
anyone has any other tips please let me know as soon as possible

-- 

Charles Riley HT(ASCP)CM

Histopathology Coordinator/ Mohs**********************

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