Check fixation time and specially IF the Bx was left to dry before fixation.René
On Thursday, July 12, 2018 12:38:28 PM, Charles Riley via Histonet <histonet@lists.utsouthwestern.edu> wrote: My pathologists says that 1 out of 100 (his estimate) of our FNA's cellblocks apears to be "cooked" when looking at the slides. The process has never been changed and all reagents are the same all the time. What is/are the possible cause(s) and what can be done to prevent this 1 out of 100 situation? -- Charles Riley BS HT, HTL(ASCP)CM Histopathology Coordinator/ Mohs _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet | | Virus-free. www.avast.com | _______________________________________________ Histonet mailing list Histonet@lists.utsouthwestern.edu http://lists.utsouthwestern.edu/mailman/listinfo/histonet