While it doesn't seem to be the convention in this group, now that I have graduated from lurking to participating, I thought I should say why I am here.
I have a new job with a genomics company in Silicon Valley, and my remit is to work out how best to represent both scientific knowledge about genomics, and also the per-patient knowledge found in say a VCF file …. Having been working in SemWeb for over a decade now (RDF Concepts, OWL Tests, Jena, Named Graphs, TopBraid Suite), my bias is to use SemWeb technologies; but, particularly with the variant information, the back-of-an-envelope numbers look fairly large, see: http://lists.w3.org/Archives/Public/semantic-web/2013Mar/0048.html (That's 1B triples for science, and 1B triples per vcf file uploaded) The Clinical Pharmacogenomics TF seems like the most relevant part, unfortunately the 7.15 - 8.15 slot for the call coincides with some parental duties for me … I am still on the look out for some documentation by people who have been tackling similar problems. As far as I can tell, many people in the field are bought into an ontological approach, but the penetration of even pretty basic SemWeb good practices is low: e.g. use of URIs for concepts, RDF and OWL … and interoperating with various large datasets (e.g. dbsnp) is necessary, but most are not natively OWL Any thoughts or suggestions would be very welcome Jeremy
