I am very much interested in this conversation. The Marshfield team is looking into using a smartphone platform for patients to collect patient-reported outcomes (PRO) for clinical use. Our use cases are for cancer and neurology patients. Your inputs are welcome!
The ontology will make the data collection integratable. Simon ================================================== Simon Lin, MD | Director, Biomedical Informatics Research Center | Marshfield Clinic Research Foundation | 1000 N Oak Ave, Marshfield, WI 54449 | 715-221-7299 | lin.si...@mcrf.mfldclin.edu | www.marshfieldclinic.org/birc From: Kerstin Forsberg [mailto:kerstin.l.forsb...@gmail.com] Sent: Friday, July 12, 2013 11:30 AM To: Luciano, Joanne S. Cc: public-semweb-lifesci hcls; Brendan Ashby Subject: Re: Encoding the Hamilton Depression Rating Scale…. See also DDI for "data from the social, behavioral, and economic sciences." http://www.ddialliance.org/Specification/RDF/Discovery We had a short call with the folks behind it (and the related RDF Data Cube) in reviewing the CDISC2RDF schema. It would be great to see the different options applied as RDF side by side. That is both the standard and instances of clinical data. As a example to discuss pros/cons etc. Kerstin Sent from my iPhone On 12 jul 2013, at 11:52, "Luciano, Joanne S." <luci...@rpi.edu<mailto:luci...@rpi.edu>> wrote: On Jul 10, 2013, at 11:37 PM, Kerstin Forsberg <kerstin.l.forsb...@gmail.com<mailto:kerstin.l.forsb...@gmail.com>> wrote: Hi Joanne, I'm intrerested in learning more about SIO and it's potential for clinical data. Michel is the expert on SIO. The web page is here: http://code.google.com/p/semanticscience/wiki/SIO I can tell you more after we encode the Hamilton Scale. Thanks very much for the link below. I will pass it along to my student. Kind regards, Joanne I can think of two related, and quite, different approaches: - CDISC provide some pieces of standards for questionnaires, such as Hamilton scale (e.g.. the list of text strings to identify different questions http://evs.nci.nih.gov/ftp1/CDISC/Questionnaire/QS%20Terminology.html), A FDA/Phuse project for Semantic Technology work on representing these pieces in RDF (http://cdisc2rdf.com/). CDISC together with TransCelerate BioPharma plan to tie the different pieces of together for measurements and questionaries as so called "Scientific Concepts" as part of thw SHARE project (http://www.cdisc.org/cdisc-share) - At ICBO eralier this week presented Alan Ruttenberg with collegues in Buffalo an interesting paper on a OBO Foundry based approach for another clinical instrument, i,e the Mini Mental Scale (MMSE), "Measuring Cognitive Functions: Hurdles in the Development of the NeuroPsychological Testing Ontology" http://www.unbsj.ca/sase/csas/data/ws/icbo2013/papers/research/icbo2013_submission_46.pdf Kind Regards Kerstin 2013/7/10 Luciano, Joanne S. <luci...@rpi.edu<mailto:luci...@rpi.edu>> Looking for some thoughts on this… We're creating an ontology for the hamilton depression rating scale (this is the clinical instrument used in all clinical trials of antidepressants). Would it be good to build this under SIO? if so, where i think it fits, is under process (the depression treatment is a process) process-> interaction->observation-> adding sub classes there instrument clinical instrument Hamilton Depression Rating Scale HDRS 28 Question Version Q1-Depressed mood [etc] does this make sense to you? do you have a better idea? Thanks, Joanne ______________________________________________________________________ The contents of this message may contain private, protected and/or privileged information. If you received this message in error, you should destroy the e-mail message and any attachments or copies, and you are prohibited from retaining, distributing, disclosing or using any information contained within. Please contact the sender and advise of the erroneous delivery by return e-mail or telephone. Thank you for your cooperation.
