Re: [Histonet] Negative Reagent Control in Diagnostic IHC Testing

[WILLIAM DESALVO]

Thanks for the great information. Downloaded and being shared w/ my lab.






Sent from Windows Mail





From: Cartun, Richard
Sent: ‎Monday‎, ‎April‎ ‎14‎, ‎2014 ‎4‎:‎04‎ ‎PM
To: histonet





For those of you who are interested, I have an Editorial in the March issue 
(Volume 22, Number 3) of Applied Immunohistochemistry & Molecular Morphology 
titled, "Negative Reagent Controls in Diagnostic Immunohistochemistry:  Do We 
Need Them?  An Evidence-based Recommendation for Laboratories Throughout the 
World".  You can download a "Free" PDF copy using the Journal's website.

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 972-1596 Office
(860) 545-2204 Fax
richard.car...@hhchealth.org


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RE: [Histonet] Negative Reagent Control in Diagnostic IHC Testing

[joelle weaver]

Fabulous, thanks. This change is on my list for 2014.




Joelle Weaver MAOM, HTL (ASCP) QIHC
 
> From: richard.car...@hhchealth.org
> To: histonet@lists.utsouthwestern.edu
> Date: Mon, 14 Apr 2014 23:03:37 +
> Subject: [Histonet] Negative Reagent Control in Diagnostic IHC Testing
> 
> For those of you who are interested, I have an Editorial in the March issue 
> (Volume 22, Number 3) of Applied Immunohistochemistry & Molecular Morphology 
> titled, "Negative Reagent Controls in Diagnostic Immunohistochemistry:  Do We 
> Need Them?  An Evidence-based Recommendation for Laboratories Throughout the 
> World".  You can download a "Free" PDF copy using the Journal's website.
> 
> Richard
> 
> Richard W. Cartun, MS, PhD
> Director, Histology & Immunopathology
> Director, Biospecimen Collection Programs
> Assistant Director, Anatomic Pathology
> Hartford Hospital
> 80 Seymour Street
> Hartford, CT  06102
> (860) 972-1596 Office
> (860) 545-2204 Fax
> richard.car...@hhchealth.org<mailto:richard.car...@hhchealth.org>
> 
> 
> This e-mail message, including any attachments, is for the sole use of the 
> intended recipient(s) and may contain confidential and privileged 
> information. Any unauthorized review, use, disclosure, or distribution is 
> prohibited. If you are not the intended recipient, or an employee or agent 
> responsible for delivering the message to the intended recipient, please 
> contact the sender by reply e-mail and destroy all copies of the original 
> message, including any attachments.
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[Histonet] Negative Reagent Control in Diagnostic IHC Testing

[Cartun, Richard]

For those of you who are interested, I have an Editorial in the March issue 
(Volume 22, Number 3) of Applied Immunohistochemistry & Molecular Morphology 
titled, "Negative Reagent Controls in Diagnostic Immunohistochemistry:  Do We 
Need Them?  An Evidence-based Recommendation for Laboratories Throughout the 
World".  You can download a "Free" PDF copy using the Journal's website.

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 972-1596 Office
(860) 545-2204 Fax
richard.car...@hhchealth.org


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are not the intended recipient, or an employee or agent responsible for 
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RE: [Histonet] Negative Reagent Control

[Smith, Allen]

For the last couple of years, I've thought this was true, but I didn't have the 
guts to say so. Thank you, Richard for bringing the truth out and getting it 
accepted.

Allen A. Smith, Ph.D.
Professor of Anatomy
Barry University School of Podiatric Medicine
Miami Shores, FL

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu 
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Richard Cartun
Sent: Tuesday, July 17, 2012 7:05 PM
To: Histonet
Subject: [Histonet] Negative Reagent Control

Most of you know that I have been advocating for the elimination of the 
"Negative Reagent Control" when using a non-avidin-biotin detection system 
(polymer) in immunohistochemical testing.  In my opinion, it is a waste of 
healthcare dollars and, more importantly, precious patient specimen.  Last year 
at the NSH IHC Forum in Denver I met James Dvorak, MT(ASCP) from the College of 
American Pathologists.  We had a long discussion about this and he agreed to 
support my position within CAP.  With the support of James, and the help of Dr. 
Regan Fulton (from the CAP IHC Committee), the wording on the CAP Anatomic 
Pathology checklist for question ANP.22570 will be changed.  The new wording 
includes the following sentence:

"Immunohistochemical tests using polymer-based detection systems (biotin-free) 
are sufficiently free of background reactivity to obviated the need for a 
negative reagent control and such controls may be omitted at the discretion of 
the laboratory director."

I announced this change at the 2012 NSH IHC/ISH Forum this past weekend in 
Windsor, CT to "loud applause".  This one change stands to save the healthcare 
system millions of dollars.  Thank you Jim and Dr. Fulton for making this 
happen!

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs Assistant Director, Anatomic 
Pathology Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax



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RE: [Histonet] Negative Reagent Control

[Chiriboga, Luis]

Outstanding!!

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu 
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Richard Cartun
Sent: Tuesday, July 17, 2012 7:05 PM
To: Histonet
Subject: [Histonet] Negative Reagent Control

Most of you know that I have been advocating for the elimination of the 
"Negative Reagent Control" when using a non-avidin-biotin detection system 
(polymer) in immunohistochemical testing.  In my opinion, it is a waste of 
healthcare dollars and, more importantly, precious patient specimen.  Last year 
at the NSH IHC Forum in Denver I met James Dvorak, MT(ASCP) from the College of 
American Pathologists.  We had a long discussion about this and he agreed to 
support my position within CAP.  With the support of James, and the help of Dr. 
Regan Fulton (from the CAP IHC Committee), the wording on the CAP Anatomic 
Pathology checklist for question ANP.22570 will be changed.  The new wording 
includes the following sentence:

"Immunohistochemical tests using polymer-based detection systems (biotin-free) 
are sufficiently free of background reactivity to obviated the need for a 
negative reagent control and such controls may be omitted at the discretion of 
the laboratory director."

I announced this change at the 2012 NSH IHC/ISH Forum this past weekend in 
Windsor, CT to "loud applause".  This one change stands to save the healthcare 
system millions of dollars.  Thank you Jim and Dr. Fulton for making this 
happen!

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs Assistant Director, Anatomic 
Pathology Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax



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RE: [Histonet] Negative Reagent Control

[Martha Ward-Pathology]

What wonderful news


 
Martha Ward, MT (ASCP) QIHC
Manager

Molecular Diagnostics Lab
Medical Center Boulevard  \  Winston-Salem, NC 27157
p 336.716.2109  \  f 336.716.5890  
mw...@wakehealth.edu  
 
 



-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu 
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Angela Bitting
Sent: Wednesday, July 18, 2012 7:26 AM
To: Richard Cartun; Histonet
Subject: Re: [Histonet] Negative Reagent Control

Our Prayers have been answered!!!

>>> Richard Cartun  7/17/2012 7:04 PM >>>
Most of you know that I have been advocating for the elimination of the 
"Negative Reagent Control" when using a non-avidin-biotin detection system 
(polymer) in immunohistochemical testing.  In my opinion, it is a waste of 
healthcare dollars and, more importantly, precious patient specimen.  Last year 
at the NSH IHC Forum in Denver I met James Dvorak, MT(ASCP) from the College of 
American Pathologists.  We had a long discussion about this and he agreed to 
support my position within CAP.  With the support of James, and the help of Dr. 
Regan Fulton (from the CAP IHC Committee), the wording on the CAP Anatomic 
Pathology checklist for question ANP.22570 will be changed.  The new wording 
includes the following sentence:

"Immunohistochemical tests using polymer-based detection systems (biotin-free) 
are sufficiently free of background reactivity to obviated the need for a 
negative reagent control and such controls may be omitted at the discretion of 
the laboratory director."

I announced this change at the 2012 NSH IHC/ISH Forum this past weekend in 
Windsor, CT to "loud applause".  This one change stands to save the healthcare 
system millions of dollars.  Thank you Jim and Dr. Fulton for making this 
happen!

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs Assistant Director, Anatomic 
Pathology Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax



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Re: [Histonet] Negative Reagent Control

[Angela Bitting]

Our Prayers have been answered!!!

>>> Richard Cartun  7/17/2012 7:04 PM >>>
Most of you know that I have been advocating for the elimination of the 
"Negative Reagent Control" when using a non-avidin-biotin detection system 
(polymer) in immunohistochemical testing.  In my opinion, it is a waste of 
healthcare dollars and, more importantly, precious patient specimen.  Last year 
at the NSH IHC Forum in Denver I met James Dvorak, MT(ASCP) from the College of 
American Pathologists.  We had a long discussion about this and he agreed to 
support my position within CAP.  With the support of James, and the help of Dr. 
Regan Fulton (from the CAP IHC Committee), the wording on the CAP Anatomic 
Pathology checklist for question ANP.22570 will be changed.  The new wording 
includes the following sentence:

"Immunohistochemical tests using polymer-based detection systems (biotin-free) 
are sufficiently free of background reactivity to obviated the need for a 
negative reagent control and such controls may be omitted at the discretion of 
the laboratory director."

I announced this change at the 2012 NSH IHC/ISH Forum this past weekend in 
Windsor, CT to "loud applause".  This one change stands to save the healthcare 
system millions of dollars.  Thank you Jim and Dr. Fulton for making this 
happen!

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax



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to it, if any) is confidential and may be legally privileged. It is intended 
solely for the addressee. Access to this message by anyone else is 
unauthorized. If you are not the intended recipient, any disclosure, copying, 
distribution or any action taken, or omitted to be taken, in reliance on it is 
prohibited and may be unlawful. If you have received this message in error, 
please delete all electronic copies of this message (and the documents attached 
to it, if any), destroy any hard copies you may have created and notify me 
immediately by replying to this email. Thank you.

Geisinger Health System utilizes an encryption process to safeguard Protected 
Health Information and other confidential data contained in external e-mail 
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instructing them to sign on to the Geisinger Health System Secure E-mail 
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RE: [Histonet] Negative Reagent Control

[Weems, Joyce K.]

Wow!! Thank you, Richard et al!! I'm doing a joy, joy dance!!!

May we begin eliminating now or must we wait for the official change?

Joyce Weems
Pathology Manager
678-843-7376 Phone
678-843-7831 Fax
joyce.we...@emoryhealthcare.org



www.saintjosephsatlanta.org
5665 Peachtree Dunwoody Road
Atlanta, GA 30342

This e-mail, including any attachments is the property of Saint Joseph's 
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regarding the error in a separate email.

-Original Message-
From: histonet-boun...@lists.utsouthwestern.edu 
[mailto:histonet-boun...@lists.utsouthwestern.edu] On Behalf Of Richard Cartun
Sent: Tuesday, July 17, 2012 7:05 PM
To: Histonet
Subject: [Histonet] Negative Reagent Control

Most of you know that I have been advocating for the elimination of the 
"Negative Reagent Control" when using a non-avidin-biotin detection system 
(polymer) in immunohistochemical testing.  In my opinion, it is a waste of 
healthcare dollars and, more importantly, precious patient specimen.  Last year 
at the NSH IHC Forum in Denver I met James Dvorak, MT(ASCP) from the College of 
American Pathologists.  We had a long discussion about this and he agreed to 
support my position within CAP.  With the support of James, and the help of Dr. 
Regan Fulton (from the CAP IHC Committee), the wording on the CAP Anatomic 
Pathology checklist for question ANP.22570 will be changed.  The new wording 
includes the following sentence:

"Immunohistochemical tests using polymer-based detection systems (biotin-free) 
are sufficiently free of background reactivity to obviated the need for a 
negative reagent control and such controls may be omitted at the discretion of 
the laboratory director."

I announced this change at the 2012 NSH IHC/ISH Forum this past weekend in 
Windsor, CT to "loud applause".  This one change stands to save the healthcare 
system millions of dollars.  Thank you Jim and Dr. Fulton for making this 
happen!

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs Assistant Director, Anatomic 
Pathology Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax



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[Histonet] Negative Reagent Control

[Richard Cartun]

Most of you know that I have been advocating for the elimination of the 
"Negative Reagent Control" when using a non-avidin-biotin detection system 
(polymer) in immunohistochemical testing.  In my opinion, it is a waste of 
healthcare dollars and, more importantly, precious patient specimen.  Last year 
at the NSH IHC Forum in Denver I met James Dvorak, MT(ASCP) from the College of 
American Pathologists.  We had a long discussion about this and he agreed to 
support my position within CAP.  With the support of James, and the help of Dr. 
Regan Fulton (from the CAP IHC Committee), the wording on the CAP Anatomic 
Pathology checklist for question ANP.22570 will be changed.  The new wording 
includes the following sentence:

"Immunohistochemical tests using polymer-based detection systems (biotin-free) 
are sufficiently free of background reactivity to obviated the need for a 
negative reagent control and such controls may be omitted at the discretion of 
the laboratory director."

I announced this change at the 2012 NSH IHC/ISH Forum this past weekend in 
Windsor, CT to "loud applause".  This one change stands to save the healthcare 
system millions of dollars.  Thank you Jim and Dr. Fulton for making this 
happen!

Richard

Richard W. Cartun, MS, PhD
Director, Histology & Immunopathology
Director, Biospecimen Collection Programs
Assistant Director, Anatomic Pathology
Hartford Hospital
80 Seymour Street
Hartford, CT  06102
(860) 545-1596 Office
(860) 545-2204 Fax



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