Dear Colleagues,

This is a reminder that applications are still open forBIOCRYS 2014 "Fundamentals of Modern Methods in Biocrystallography" organised by Maria Armenia Carrondo and Thomas R. Schneider. Closing date for applications is the 15th July.
*Course sponsored by :* FEBS, BioStruct-X and IUBMB
*
**Date & Location:*20th - 27th September 2014 at the Instituto de Tecnologia Química e Biológica, Oeiras, Portugal.

Topics of the course will run from fundamentals such as symmetry, point groups and crystal systems, basic diffraction physics, reciprocal space and the Ewalds sphere, radiation damage, data processing, symmetry in the diffraction pattern, structure factors, Patterson function to modern methodologies including molecular replacement, SAD, MAD, MIR and maximum likelihood phasing, direct methods, density modification, refinement, model building, twinning and structure validation. Main challenges on sample preparation and crystallization of proteins will also be covered. The course will be organized with lectures in the mornings and interactive practicals and tutorials in the afternoons. Evening lectures will address two main important topics within Structural Biology, one covering studies of membrane proteins and the other the beginning of the use of free electron lasers in Macromolecular Crystallography. Participants will be limited to 36, aimed primarily at people at the beginning of their crystallographic research activity as PhD students or others. Selected applicants are invited to present a poster during the course.

*Speakers and tutors: *

*Margarida Archer*ITQB, Oeiras, PT
*Isabel Bento*ITQB, Oeiras, PT
*Gabor Bunkoczi *University of Cambridge, UK
*Kevin Cowtan*University of York, UK
*Zbigniew Dauter*Argonne National Laboratory, USA*
Kristina*/*Djinovic-*//*Carugo*//, University of Vienne, AT/
*Carlos Frazão*ITQB, Oeiras, PT
*Elspeth Garman*University of Oxford, UK
*Gordon Leonard*ESRF, Grenoble, FR
*Andrew Leslie*MRC LMB, Cambridge, UK
*Bernhard Lohkamp *Karolinska Institutet, SE
*Adrian Mancuso*European XFEL GmbH, Hamburg, DE*
Rob Meijers,*EMBL-Hamburg, DE
*Pedro Matias*ITQB, Oeiras, PT*
Poul Nissen*, University of Aarhus, DK
*Anastassis Perrakis*NKI, Amsterdam, NL
*Célia Romão*ITQB, Oeiras, PT
*Thomas Schneider,*EMBL-Hamburg, DE*
Philip Willmott*, Paul Scherrer Institut, CH
*Clemens Vonrhein*Global Phasing Ltd, Cambridge, UK


*How to apply:*
A registration fee of 650 Euros for academic and 1200 Euros for non-academic applicants is requested for full board and accommodation. Selected applicants will have to pay the registration fee by bank transfer before arrival.

A limited number of grants are available from FEBS.

For an application, please fill the form on the web page by the 15th of July.

For more information visit the course web page http://biocrys2014.itqb.unl.pt/

We look forward to welcoming you to Oeiras


--
*Colin E. McVey, DPhil*

Principal Investigator
Structural Virology Lab
Macromolecular Crystallography Unit
Instituto de Tecnologia Química e Biológica
Av. da Republica, EAN          | Phone:(351)214469663
Apartado 127                  | Fax :(351)214433644
2781-901 Oeiras              | email:mc...@itqb.unl.pt
PORTUGAL

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