Dear Wei,
doesnt sound too special to me. DNA in itself is a very soluble
molecule. The part which hangs out of
the core complex drives solubility of the whole thing.
As a drawback crystallizability may also go down...
All the best,
Matthias
-
Dr. Mat
Dear CCP4er,
I have an interesting observation for one of my DNA binding protein--when the
length of DNA flanking both DNA binding site increase, the solubility of
protein-DNA complex increases. And I can get a nice sigmoid curve from protein
solubility versus DNA length. The solubility of prot
