Re: [ccp4bb] disulfide bond question

2011-04-05 Thread Zhijie Li
density for the C155 seems too weak to support the C155-C157 linkage. Guess this one should not be counted. Zhijie -- From: "Heping Zheng" Sent: Tuesday, April 05, 2011 5:00 PM To: Subject: Re: [ccp4bb] disulfide bond question Ronn

Re: [ccp4bb] disulfide bond question

2011-04-05 Thread Heping Zheng
Ronnie -- The list that I have in a home database contains 89 instances of a CXC in 53 files when C-C forms a disulfide bond. The records returned are ordered by the name of "X" residue from CXC motif for convenience. There is indeed PRO in one case (2zxt), but it is not the major observation in

Re: [ccp4bb] disulfide bond question

2011-04-05 Thread Allister Crow (JIC)
Ronnie, There are several. The example I know is 1DBI - I have little doubt that there are more out there... If you are interested by the close proximity in sequence then you might also like to know that there are examples of 'CC' motifs with disulfides - look at 1KB0 - a PQQ-dependant alco

[ccp4bb] disulfide bond question

2011-04-05 Thread Ronnie
I have a question related to protein structure, but not crystallography per se. Has anyone see a disulfide forming between the two cys of "CXC" in the middle of a loop, and create a sharp turn, where X is not a proline? I seems to me that geometrically this would be possible but I am not sure h