Hi, Randy, I've been taking Lyrica and Lexapro for quite awhile but just changed over to Cymbalta from the Lexapro and added Tramadol for pain and I can't tell you how much I've improved! I experimented with the timing on taking the Tramadol and only take two a day. You can take 1-2 up to 4 times a day (800mg total) and I'm only taking 1 in the AM and 1 at noon. The Cymbalta is an antidepressant but also seems to help with pain so that is why we changed over to that from the Lexapro.
Gosh, I sure wish it could help someone else... Jeanne