Hi Vilius. You can restrict the phi_ex/k_ex with value.set before grid search. It will though be set free again in minimisation.
For case 2. Try to set the INSIGNIFICANCE to 0. Best Troels 2016-04-19 11:54 GMT+02:00 Vilius Kurauskas <vilius.kuraus...@ibs.fr>: > Dear Sirs and Mesdames, > > I am fitting my data with M61 model with relax. There is a somehow loosely > defined canonical site in the protein, for which we know approximately the > exchange parameters. However, there are more residues showing relaxation > dispersion profiles and I would like to know if these residues could also > belong to the canonical site. > To address this problem, I have implemented a simple jackknifing procedure > which precedes the fitting. Unfortunately, I very often encounter a > situation where unrealistically high phi_ex values are fitted, resulting in > very low exchange rates. I would like to restrict the phi_ex/k_ex values > (either to a constant or to an interval of values) and compare the fit > results manually. > However, I was not able to find in the Relax tutorial if such a function > exists for R1rho relaxation dispersion models (I am using scripts to run > Relax). > > Furthermore, I have encountered sometimes a situation where a flat line is > fit to a data clearly showing relaxation dispersion, which is higher that > the set INSIGNIFICANCE (I assume phi_ex is set to 0). Is there any > explanation for that? > > Thank you very much in advance and I apologize if my formulation was not > very clear (I am a biologist and just relatively recently got into this > stuff). > > vilius > > _______________________________________________ > relax (http://www.nmr-relax.com) > > This is the relax-users mailing list > relax-users@gna.org > > To unsubscribe from this list, get a password > reminder, or change your subscription options, > visit the list information page at > https://mail.gna.org/listinfo/relax-users > _______________________________________________ relax (http://www.nmr-relax.com) This is the relax-users mailing list relax-users@gna.org To unsubscribe from this list, get a password reminder, or change your subscription options, visit the list information page at https://mail.gna.org/listinfo/relax-users
