[ccp4bb] CBMS Lecture Series - Dr Sibel Yalcin - March 16, 13:30, DST

2022-03-14 Thread Stojanoff, Vivian
Please join us…… Sidel Yalcin Yale University WEDNESDAY, MARCH 16, 13:30 (DST) "Electrogenetic Control of Bacteria via Protein Nanowires Capable of Ultrafast Charge Transport and Storage for Next-Generation of Bioelectronic Materials and Devices" Register in advance for this

Re: [ccp4bb] mysterious density

2022-03-14 Thread Diana Tomchick
Contour the 2Fo-Fc map at lower sigma than 1.3, and see if the resulting density looks like MES. As others have said, if there is no specific pocket or interactions for the non-sulfonic acid head group, then I would expect that density to be weaker or smeared out due to positional disorder.

Re: [ccp4bb] Ligand occupancy refinement

2022-03-14 Thread Pavel Afonine
For the record, occupancy refinement scenario you're looking for is described here: https://phenix-online.org/phenixwebsite_static/mainsite/files/newsletter/CCN_2015_07.pdf#page=12 Cheers, Pavel On Thu, Mar 3, 2022 at 7:09 AM Jon Cooper < 488a26d62010-dmarc-requ...@jiscmail.ac.uk> wrote: >

Re: [ccp4bb] Ligand occupancy refinement

2022-03-14 Thread Steven Herron
Dear Akanksha, When you re-do the occupancy refinement, don't include a b-factor refinement along with the occupancy refinement.  Do them separately. Do one, then do the other, and then repeat until convergence. If your B-factor values are either high or low, the computer will try to

[ccp4bb] Scientist in Structural Biology - Halic Lab

2022-03-14 Thread Bilokapic, Silvija
Scientist in Structural Biology - Halic Lab This is an exciting opportunity for a self-motivated scientist to join the Structural Biology Department at SJCRH in the laboratory of Dr. Mario Halic. The Halic lab studies the epigenetic regulation of gene expression using genetics, molecular

[ccp4bb] PhD studentship in time resolved crystallography of multifunctional enzymes using synchrotron and XFEL facilities

2022-03-14 Thread Hough, Michael (DLSLtd,RAL,LSCI)
Dear all, We have extended the deadline for the studentship and will now consider applications as they are received with no fixed closing dates. I will be very grateful if you could pass this on to any potentially interested candidates. We have a fully funded four year PhD studentship

[ccp4bb] Research Assistant - UCB (UK)

2022-03-14 Thread Leysen Seppe
Hi everyone We're looking for a Research Assistant in our Protein Structure & Biophysics team. This is a contract position (12 months). Please see below for a detailed job description. If you currently have the right to work in the UK and wish to apply, send your CV and cover letter to

[ccp4bb] contract position - Protein Purification Scientist - UCB (UK)

2022-03-14 Thread Leysen Seppe
Hi everyone Do you enjoy protein purification, and can you operate an AKTA to run IMAC, IEX and SEC protein purifications without supervision? Do you want an opportunity to learn about antibody and small molecule drug discovery? Then check out our contract position (12 months, starting asap)