HYDERABAD, December 12, 2014
Stem cells in eye can restore vision, say scientists
T. Lalith Singh
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In what promises to be an alternative to corneal transplantation in
treating blindness caused from damage to cornea, scientists from
city-based L.V. Prasad Eye Institute (LVPEI) in collaboration with
U.S. scientists claimed to have discovered potent stem cells in the
eye that possess the ability to restore lost sight.

The findings have been published in the journal, Science Translational
Medicine on Thursday. Speaking to journalists, Sayan Basu, LVPEI
consultant corneal surgeon and scientist, said he along with other
scientists at the laboratory of Prof.James L.Funderburgh, Professor of
Ophthalmology, University of Pittsburgh School of Medicine, tested
stem cells obtained from human eyes on an experimental model of
corneal scarring.

"We found that when these stem cells were applied to damaged cornea
they healed and became clear again within four weeks of treatment,"
Dr. Basu said.

These stem cells also appeared to have induced healing beyond
immediate vicinity and suggested they produce factors that promote
regeneration and not just replacing the lost tissue, he said.

Using stem cells could change the existing paradigm of treatment
corneal blindness through transplantation, which not only needed
sutures but also entailed a donor and the list of waiting recipients
running long.

Dr.Basu hopes the new finding would change this as the stem cells
could easily be obtained from the patients with corneal scarring and
then used therapeutically in the same person's eyes.

This is achieved by simply layering the cells over the damaged areas
with biological adhesive called fibrin glue, he explained.

Claim that it can be an alternative to corneal transplantation


Source: 
http://www.thehindu.com/todays-paper/tp-national/stem-cells-in-eye-can-restore-vision-say-scientists/article6684436.ece

Comments to: web.thehi...@thehindu.co.in  Copyright(c) 2014, The Hindu



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