Hi Jiang.

You need to take the log2 of the residuals. CEL files store only positive numbers.

This question has been answered many times. For starters, have a look at:
http://www.mail-archive.com/aroma-affymetrix@googlegroups.com/msg01015.html

Cheers,
Mark

On 8-Jan-10, at 2:53 AM, camelbbs wrote:

Hi,
can anyone help?
Jiang

On Jan 5, 9:47 am, camelbbs <camel...@gmail.com> wrote:
HI,
I found the FIRMA scores are all >0, so what do you mean the
positive or negative? and i am not very understand this sentence "it
seems logical to find FIRMA scores that are different b/w your 2+
groups". That if there are several samples in each group, how to deal
with it?
Thanks,
Jiang
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Mark Robinson, PhD (Melb)
Epigenetics Laboratory, Garvan
Bioinformatics Division, WEHI
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e: mrobin...@wehi.edu.au
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When reporting problems on aroma.affymetrix, make sure 1) to run the latest 
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