I have changed a lot of my setup in the past months and am using DPM from
microsoft on our server 2003 and 2008 infrastructure.  I used to use
backuppc but it is not the best tools for windows servers.  DPM can do
rolling backups in 15 minute intervals and has some nice client side agents
to do such things with volume shadow copy.

I do have a virtualization cluster running on proxmox ve with 3 vm hosts and
1 SAN (migrated off of citrix xenserver, which works great until it crashes
and requires complete restores of all VMs) and I use backuppc for the entire
cluster (vm hosts and actual virtual machines).  I am using both the openvz
containers for services like bind, dhcp, mysql, and web servers and use KVM
for higher level stuff like specific windows apps on xp pro vms) I do all
logins for the whole linux cluster via LDAP specifically to make sure UID
and GID are the same across every machine.  With the centralized
authentication and accounting, I setup a backupagent user on each machine
and give it sudo rights to rsync and limit logins to that user account by
host (the backuppc servers, specifically).

I have a single backuppc machine backing up each server which is my 'stable
setup' and then I have a secondary " test cluster" of 2 backuppc machine
with DRDB syncing up the raid1 array between the two hosts.  one machine is
a primary and the other rsyncs the backuppc config over so they are
identical but does not run backuppc.  This link is over a 10Mbit wan link
from my colo to my office (same ISP, nice) and is so far a wildly successful
experiment running drdb with ssh compression over a WAN link.  DRDB does a
very good job and 'catching up' to the relatively slow WAN link.  I have
found that backuppc uses bandwidth in a pulsing fashion with high and low
moments witch lets drdb gain ground during the lulls in bandwidth usage.
(measured with iftop on the LAN interface and the WAN interface, and
watching the WAN stay saturated and the LAN pulse)

I have another backuppc machine that is backing up windows xp clients with
deltacopy(essentially cwrsync).  maybe 25 or so hosts on this machine.  I
backup the entire "documents and settings" folder.  I use microsofts ximage
to pull whole base level system images so I can restore that and dump the
settings and files back over the top.

anyway, I am successfully using backuppc for production and am doing
off-site replication and have done remote restores across WAN links.  my
setup is constantly evolving as we migrate away from our old equipment on to
more modern hardware and software.

good luck.
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