Penggunaan ibuprofen jg ada dosisnya, sebesar 5-10 mg/kg/kali mempunyai efektifitas antipiretik yang setara dengan aspirin atau parasetamol. Ibuprofen bisa menyebabkan ulkus lambung, perdarahan, dan perforasi, meskipun komplikasi ini jarang pada anak-anak. Ibuprofen juga tidak direkomendasikan untuk anak demam yang mengalami diare dengan atau tanpa muntah.
Shg utk anak demam, parasetamol adalah obat pilihan pada anak-anak. Dosisnya sebesar 10-15mg/kg/kali. Parasetamol dikonjugasikan di hati menjadi turunan sulfat dan glukoronida, tetapi ada sebagian kecil dimetabolisme membentuk intermedietaril yang hepatotoksik (menjadi racun untuk hati) jika jumlah zat hepatotoksik ini melebihi kapasitas hati untuk memetabolismenya dengan glutation atau sulfidril lainnya (lebih dari 150 mg/kg). Maka sebaiknya tablet 500 mg tidak diberikan pada anak-anak (misalnya pemberian tiga kali tablet 500 mg dapat membahayakan bayi dengan berat badan di bawah 10 kg). Kemasan berupa sirup 60 ml Lebih detail ttg ibuprofen, bisa ke http://www.drugs.com/ibuprofen.html Ibuprofen Generic Name: ibuprofen (eye byoo PROE fen) Brand Names: Advil, Genpril, Ibu-200, Midol, Motrin, Nuprin What is ibuprofen? Ibuprofen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing hormones that cause inflammation and pain in the body. Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. Ibuprofen may also be used for other purposes not listed in this medication guide Important information about ibuprofen This medicine can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use ibuprofen. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG). Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance. This medicine can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking ibuprofen. Older adults may have an even greater risk of these serious gastrointestinal side effects. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. Do not take more of this medication than is recommended. An overdose of ibuprofen can cause damage to your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). Use only the smallest amount of this medication needed to get relief from your pain, swelling, or fever. Avoid taking ibuprofen if you are taking aspirin to prevent stroke or heart attack. Ibuprofen can make aspirin less effective in protecting your heart and blood vessels. If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take the aspirin (non-enteric coated form). Do not drink alcohol while taking this medication. Alcohol can increase your risk of stomach bleeding caused by ibuprofen. Before taking ibuprofen Taking an NSAID such as ibuprofen can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG). NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects. Do not use this medication if you are allergic to ibuprofen, aspirin or other NSAIDs. Before taking this medication, tell your doctor if you are allergic to any drugs, or if you have: * a history of heart attack, stroke, or blood clot; * heart disease, congestive heart failure, high blood pressure; * a history of stomach ulcers or bleeding; * asthma; * polyps in your nose; or * liver or kidney disease, * systemic lupus erythematosus (SLE); * a bleeding or blood clotting disorder; or * if you smoke. If you have any of these conditions, you may need a dose adjustment or special tests to safely take ibuprofen. FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby during early pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. However, taking ibuprofen during the last 3 months of pregnancy may result in birth defects. Do not take this medication during pregnancy unless your doctor has told you to. It is not known whether ibuprofen passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child without the advice of a doctor. Ibuprofen side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and seek medical attention or call your doctor at once if you have any of these serious side effects: * chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance; * black, bloody, or tarry stools; * coughing up blood or vomit that looks like coffee grounds; * swelling or rapid weight gain; * urinating less than usual or not at all; * nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); * fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; * bruising, severe tingling, numbness, pain, muscle weakness; or * fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions). Less serious ibuprofen side effects may include: * upset stomach, mild heartburn, diarrhea, constipation; * bloating, gas; * dizziness, headache, nervousness; * skin itching or rash; * blurred vision; or * ringing in your ears. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. -------------------------------------------------------------- Info tanaman hias: http://www.toekangkeboen.com Info balita: http://www.balita-anda.com Peraturan milis, email ke: peraturan_mi...@balita-anda.com menghubungi admin, email ke: balita-anda-ow...@balita-anda.com
