----- Original Message ----- 
From: "Adam & Hanni Armansyah" <[EMAIL PROTECTED]>
To: <[EMAIL PROTECTED]>
Sent: Friday, December 24, 2004 7:41 AM
Subject: [sehat] [artikel] Penarikan Pernyataan Kaitan Autisme & MMR



Dear SPs,

Mohon disimak artikel yang di-share oleh Lydia di bawah ini
tentang penarikan pernyataan tentang kaitan vaksin MMR dg Autisme.
mudah-mudahan bisa menyeimbangkan pengetahuan kita..

Thanks ya Lyd!

salam,
/hanni

----- Original Message ----- 
From: "Iswara, Lydia M"
Sent: Monday, December 20, 2004 6:27 PM
Subject: finally....


http://www.kidshealth.org/PageManager.jsp?dn=KidsHealth&lic=1&ps=107&cat_id=4&article_set=34122


Controversial Study Withdrawn Suggesting Link Between Autism and MMR Vaccine
March 9, 2004

In 1998, Andrew Wakefield headed a group of researchers in publishing a
much-disputed study that suggested a possible link between autism and the
measles-mumps-rubella (MMR) vaccine. Since then, several studies have found
no clear evidence to link MMR and autism, and all major health
organizations - including the American Academy of Pediatrics, the National
Institutes of Health, the Centers for Disease Control and Prevention, and
the World Health Organization - have rejected Dr. Wakefield's claims. Still,
fear of the MMR vaccine has caused some parents to avoid immunizing their
children, leaving them susceptible to diseases that once killed thousands.

Now, 10 out of its 13 authors are retracting, or taking back, the
controversial 1998 study. The Lancet, the journal in which the 1998 study
was published, printed the retraction in the March 6 issue. The authors
write: "We wish to make it clear that in this paper no causal link was
established between MMR vaccine and autism as the data were insufficient.
However, the possibility of such a link was raised and consequent events
have had major implications for public health. In view of this, we consider
now is the appropriate time that we should together formally retract the
interpretation placed upon these findings in the paper."

Dr. Wakefield, who did not sign the retraction, believes that the MMR
vaccine causes abnormalities in the intestines that lead to the release of
toxic chemicals that cause autism when they reach the brain. However, most
medical experts have agreed for years that his study is critically flawed.
The most notable problems with Dr. Wakefield's 1998 study were that it:

involved only 12 children - not a large enough sampling to generalize to the
entire population
didn't use a control group - that is, it only studied autism in vaccinated
children, and didn't compare the incidence of the condition in unvaccinated
children
proposed a link between the timing of the MMR vaccine and the onset of
symptoms of autism without addressing two issues: one, that because MMR is
given around the time that autism is commonly diagnosed (12 to 15 months),
the association of the vaccine to the symptoms might be coincidental; and
two, that in several of the studied children the symptoms of autism
pre-dated the vaccination
About Autism
Autism is a developmental disorder that affects as many as one in 500 people
in the United States. Usually diagnosed in toddlers, it's characterized by
mild to severe impairment of communication and social interaction skills.
Although a specific cause of autism has not been found, several theories
exist.

Although the number of children diagnosed with autism is increasing, the
rates of MMR vaccination are not; in London, diagnosis of autistic disorders
has been on the rise since 1979 but hasn't increased since routine MMR
vaccination began in 1988. In addition, the age of diagnosis of autism has
been found to be the same whether a child receives the MMR vaccine or
doesn't. What many researchers are discovering is that subtle symptoms of
autism are often present before a child's first birthday - sometimes even in
early infancy - but often go unnoticed until the symptoms are more obvious
to parents.

So what could explain the increased rates of autism in recent years? For one
thing, a broader definition of autism that can be applied to more children
who show varying degrees of symptoms. There's also been a greater awareness
of the condition among health professionals, which has lead to more
diagnoses.

As for what causes the condition, medical experts believe it may be a
combination of factors. A genetic basis is suspected, evidenced by the fact
that the identical twin of a child with an autistic disorder will have a 92%
chance of having one, too, while a fraternal twin has only a 10% chance.
Research also points to the possibility that other factors, such as toxins
or viral infections, may cause or trigger autism before birth.

Medical researchers all over the world continue to investigate the possible
causes of autism.

Reviewed by: Steven Dowshen, MD
Date reviewed: March 2004


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