If go for python and wxwidgets you might want to check out TurboGears [ http://turbogears.org/ ], django [ http://www.djangoproject.com/ ], CherryPy [ http://www.cherrypy.org/ ] and Zope [ http://www.zope.org/ ] for web support. I think TurboGears can help you with your database driven apps otherwise the mysql and sqlite bindings are always there. For bindings search the cheese shop [ http://cheeseshop.python.org/ ], the Vaults [ http://www.vex.com/parnassus/ ] and oreilly's zoo [ http://python.codezoo.com/ ] (and of course google).
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