>
>
>That morning , Kandy came to pick me up from the Mission. Former health
>officer on the miners' union, she had been emailing me for ages since my BBC
>film about Manganese and mad cow was shown on ABC Four Corners. Kandy had
>lived on Groote with her husband for twenty years, having done the hippy 
>trail around the world back in the 1970s. Both of them had been employed in
>the mines, and she had become concerned since her own blood tests had shown
>high manganese and low magnesium.
>
>  Kandy  took me to meet a group of concerned woman in the local hall of the
>mining village at Alyangula, many of whom had young children and were
>connected to the mine in some way.
>
>This seemed a good opportunity for promoting the importance of magnesium
>supplementation as a prevention against some forms of  manganese
>intoxication. Particularly important in any children who are concieved on
>this island. For when magnesium is low and manganese is high, manganese can
>substitute itself into vacant sites on magnesium activated enzymes, with
>disastrous repercussions causing total  inactivation of those enzymes as I
>have mentioned previously..
>
>What needs to be of the greatest concern to pregnant women, is the fact that
>manganese can induce mutations in genetic material when high manganese / low
>magnesium circumstances cause an  inactivation of  the magnesium ribosomal
>enzymes - producing the genetic problem of Groote syndrome that is so widely
>seen in the Aboriginal community down the road at Angurugu. Whilst
>Aboriginals are no doubt more susceptible to this specific mutation for
>dietary and genetic reasons, the Caucasian miners could well start developing
>these and other types of mutations in their offspring. 
>
>Amazingly, the potential of  high Manganese  to invoke mutations is
>ironically being exploited in pharmacology  to positive uses in the fight to 
>suppress the AIDS syndrome. Manganese can inactivate the magnesium activated
>enzyme, reverse transcriptase, once the manganese to magnesium ration gets
>too high in cells . This deprives the HIV virus of its ability to make
>multiple copies of itself ; thereby severely suppressing the development of
>the AIDS disease process.
>
>Kandy then took  me up to the headquarters of the mine, where I had been
>scheduled for a tour and then a meeting with the big brother of the company
>!! One of the Union bosses then drove me around the different mine sites to
>view the techniques of open cast mining - felling the forest, blasting,
>stripping off the upper crust of laterites, mining the black manganese
>dioxide ore bed, backfilling, then replanting.
>
>I must say that  I was highly impressed with the replanted rainforest after
>the mining operations had been  completed. Indigenous saplings had been
>utilized, managed and maintained by Aboriginal labour until it was certain
>that the trees had taken root. I honestly could not distinguish between
>original rainforest and replanted - save the height of the trees. It was
>overtly apparent that this mining corporation was not operating like some of
>the more dubious operations at work in S America and New Quinea.
>
>In the worker's canteen I met one of the miners who was pleased to meet with
>me. He had been bereaved and left with two young children a few years earlier
>after his wife had died of a motor neurone type disease identical to that of
>the Aboriginal's Groote syndrome. Maxine had worked in the laboratory at the
>mine where I was guided to next. I met the chief chemist in the lab who
>showed me the black samples of manganese dioxide - referred to as the black
>magic metal back in Byzantine times -which they spent all day analysing .
>
>Whilst it was reasonably apparent that the mining company had been doing a
>highly impressive job
>regarding the preservation of the environment and safeguarding some of the
>socio-economic interests of the Aboriginal community, I did however feel that
>there could have been an insidious problem with the issue of airborn
>manganese being kicked up by the dust factor. Although the mine had been
>attempting to dampen down the dust from time to time with water, there were
>storage heaps and tailings heaps of manganese very close to the village of
>Angurugu ( just a few hundred metres from some houses ) and storage heaps
>around the jetty very close to the mining village of Alyangula. All residents
>had been complaining of black dust settling inside their houses - even the
>houses that had air conditioning.
>
>  It did seem to me that the problems of this community were fundamentally
>based upon the high manganese bedrock so close to the surface - with all
>local water and home grown food supplies being contaminated. But the dust
>from the mining operation had considerably exacerbated the problem. It should
>be remembered that once manganese is inhaled - like aluminium and silver, etc
>- it does not need to travel to the lungs and cross into the blood,  etc; it
>can be absorbed directly into the brain via the nasal-olfactory tract.
>
>I was then ushered into the manager's office who seemed more interested in
>tape recording every thing that I was up to for an hour whilst failing to
>divulge anything that they were up to - I could not even extract a map of the
>main manganese outcrops on Groote from them !! Nonetheless, he seemed a nice
>straight forward guy who was fresh to the job and genuinely interested in
>environmental issues surrounding metals when his company hat was off.
>
>The manager was also keen to continually direct me onto the mining company
>funded work at the Menzies School of Medicine in Darwin which had concluded
>that Groote Syndrome was solely a disease linked to the genetics of a
>specific aboriginal clan which had interbred with the Macassan sailors who
>used to visit for trepang three hundred years ago.  So why did'nt the disease
>  strike many years ago, and, furthermore,  amongst all of those other races
>around the world where the Macassans had interbred ?
>
>But I kept on reminding myself of Gayangwa lalara's  words of local wisdom on
>the first cases of Groote Syndrome. She categorically says that there was no
>Groote syndrome around  when she was a child. The first case struck her
>father which happened after they had settled full time at Angurugu and after
>the initial mining explorations had just began. The Aboriginal Elder of
>Angurugu confirmed this to me. In fact, the only people who have stated
>otherwise were the 'expert' authors of a spate of publications on studies at
>the Menzies school of  Medicine that had been funded by the mining
>corporation itself. They had alleged that the aboriginees had stated that
>Groote syndrome existed in the 18th century.  I know whose observations  I
>can trust !!
>
>I returned back to Angurugu little the wiser. Much of the manganese dioxide
>was going from this mine for incorporation into products that were being
>manufactured all over the world - bricks, steel, aluminium / uranium alloys,
>dyes, batteries, paint pigments,  animal minerals and fertilisers - other
>industries whose workforces have been associated with a raft of high
>incidence clusters of  these same classes of neurodegenerative disease.
>
>In the afternoon , we went out yamming. This entails parties of woman working
>the woodlands to track down the particular species of vine that nourishes the
>edible yam .I felt honoured to be able to push Roseanne out to the woods in
>her wheelchair -  a skeletal  33 year old victim with a stunningly beautiful
>face. Like all Aboriginal people, she just accepts her faoldte. No self pity,
>just a buddhistic way of living with her condition.  I secretly wanted to
>steal her back to the UK and somehow get her right again ! I could feel her
>pain, a few faded traces of red nail varnish still smudged across her nails,
>as though she had just about given up her final hopes of getting married and 
>living some semblance of a normal Aboriginal lifestyle.  The other women
>brought the crowbars, hatchets, and spades for digging and extracting the
>yams; whilst Gayangwa's 9 year old grandson was monkeying around through the
>mangroves with his machete, pairing back spearheads from the saplings and
>then giving a poor tree snake hell - the one I had just seen coiled up a
>tree..
>
>It was like a spiritual ceremony working with these people. Gayangwa walking
>around the forest forever staring upwards, surveying the canopy of the forest
>in order to pinpoint any tell tale signs of  the edible yam. I began to
>wonder how she was not hypnotised by the bright sunlight stroboscoping its
>way down the stringybacks to the forest floor. Where was that withered vine
>that bore the crisp, heart shaped leaves of the edible yam ? The breeze
>caught the leaves, their flipsides fluttervalving out a kind of mantra of the
>forestfloor. Every so often Gayangwa had to break off her concentration to
>scold her grandson  who was tarzaning  across our tracks on the vines .
>
>After about half an hour, one of the girls called across in Aboriginal
>language. I soon got the gist that she had found one; a scorched up vine
>which trailed downwards, going earthbound beside the roots of  a mangrove
>trunk . After alternate digging with the crowbar and then scratching the soil
>out with our barehands, we eventually uncovered the first sightings of the
>yam - laid out right across the backbone of the manganese bedrock.. As we dug
>around the rest of it, I got embarrassed when I realised that I had  ineptly
>dug the spade straight through the middle of it - its sap already exuding
>from the bruising ! 
>
>I was interested in yams, because all of the victims who I had interviewed
>had consumed them in high quantities. And  analytical tests already conducted
>  had revealed manganese at excessive levels of 1000 ppm in the yam roots. The
>women were telling me that the yams made you itch all over if you ate them
>uncooked, which made me wonder what other toxic substances could be lurking
>in their tissues - some allergic photosensitising  agent perhaps ? My
>enthusiasm and  desire to investigate this further immediately reminded me of
>my total lack of funding resources and inability to take this whole research
>any further forwards - until I had some firm offer of funding . This was very
>frustrating.
>
>As we left , I could see the poor helpless Roseanne waiting back at the
>trackside for us in her wheelchair - in desperate need for some line of hope.
>God, at her age, she deserves it, surely ? . My anger surged again , as I
>remembered the absurd , irrational and totally unscientific reasoning behind
>the British Ministry of Agriculture's rejection of my proposal for a three
>year grant funding project - which their minister had invited me to submit 
>in the public forum of a BBC film. This project could have advanced some
>major discoveries/developments into the causes and prevention of these
>diseases - for a minute percentage of the two million pound award that went
>to various conventionally acceptable professors for re-assessing 
>quesstimates of the future incidence dynamics of the vCJD epidemic - an
>epidemic which never really came !!
>
>One of the reviewers of my proposal  had misread the number of samples that I
>had proposed for each cluster location - by twenty fold less - and accused me
>of proposing too few samples per cluster location to be scientifically valid.
>If this were the case, you could just increase the number of samples to be
>taken, surely ? But despite my pointing this major error out to the Ministry,
>they  heralded this up as the key criticism, later promoting that reviewer to
>their expert panel for assessing  BSE research. Their appraisal got worse
>still; splitting hairs over the fact that I had used the term "slice" of soil
>when referring to the section of soil that is dug out with my sampling trowel
>! One of  the reviewers actually asked what  the word "slice" meant, despite
>widespread use of this term in the 'gospel' of soil sampling guidelines
>decreed in the Natural Resources Management Ltd instruction book . NRM are
>the most reputable sampling lab in the UK !! Having been falsely accused of
>not  including soil pH, redox potential in my analyses,  the Ministry also
>disapproved of my intention to use small cardboard boxes for holding the soil
>samples - the very boxes supplied by the NRM !! 
>
>Well, I suppose I should have learnt the lesson by now that the Ministries
>and their global corporations like to hide their mega manganese or organo
>phosphate interests behind farcical disputes over the suitability of
>cardboard  boxes  or the terminological confusion surrounding  soil slices. 
>But how do they have the heart to place these fastidious nit-pickings in
>front of this crippled young girl ? don't they have children themselves ? As
>my anger eventually drained itself out in the afternoon heat , I stopped
>myself short of  getting into imaginary spear and machete attacks on the
>Ministry of Agriculture's offices in London !! Was the manganese beginning to
>get to my very own serotonin receptors by now, I wondered ?
>

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