Dear Martin and List, I have a problem with linking to Rhtslib on Mac OSX when my R installation directory differs from the package installation directory. Trying to load csaw (Bioc release version) gives me:
> require(csaw) # ... whole lot of dependencies... Loading required package: csaw Error in dyn.load(file, DLLpath = DLLpath, ...) : unable to load shared object '/Users/lun01/Library/R/3.3/library/csaw/libs/csaw.so': dlopen(/Users/lun01/Library/R/3.3/library/csaw/libs/csaw.so, 6): Library not loaded: /Library/Frameworks/R.framework/Versions/3.3/Resources/library/Rhtslib/lib/libhts.0.dylib Referenced from: /Users/lun01/Library/R/3.3/library/csaw/libs/csaw.so Reason: image not found ... which is because my Rhtslib shared library is sitting instead at /Users/lun01/Library/R/3.3/library/Rhtslib/lib/libhts.0.dylib (along with all my other non-recommended, non-base packages). I presume this linking failure occurs because the Makevars file (which would normally indicate where the shared library is living) doesn't get run when installing a prebuilt binary? The same issue occurs with deepSNV, which is the other package that links to Rhtslib. Any thoughts? I don't usually use Macs, so I don't know exactly what goes on during package installation, or whether my setup (i.e., with different package/R locations) is atypical or not. Aaron > sessionInfo() R version 3.3.0 (2016-05-03) Platform: x86_64-apple-darwin13.4.0 (64-bit) Running under: OS X 10.10.5 (Yosemite) locale: [1] en_GB.UTF-8/en_GB.UTF-8/en_GB.UTF-8/C/en_GB.UTF-8/en_GB.UTF-8 attached base packages: [1] stats4 parallel stats graphics grDevices utils datasets [8] methods base other attached packages: [1] SummarizedExperiment_1.2.2 Biobase_2.32.0 [3] GenomicRanges_1.24.0 GenomeInfoDb_1.8.1 [5] IRanges_2.6.0 S4Vectors_0.10.1 [7] BiocGenerics_0.18.0 BiocInstaller_1.22.2 loaded via a namespace (and not attached): [1] AnnotationDbi_1.34.3 XVector_0.12.0 edgeR_3.14.0 [4] GenomicAlignments_1.8.0 zlibbioc_1.18.0 BiocParallel_1.6.2 [7] tools_3.3.0 DBI_0.4-1 Rhtslib_1.4.2 [10] rtracklayer_1.32.0 bitops_1.0-6 RCurl_1.95-4.8 [13] biomaRt_2.28.0 RSQLite_1.0.0 limma_3.28.5 [16] GenomicFeatures_1.24.2 Biostrings_2.40.1 Rsamtools_1.24.0 [19] XML_3.98-1.4 ______________________________________________________________________ The information in this email is confidential and intend...{{dropped:4}} _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel