Dear Satya,

All these scores do have to be calculated using substitution matrices like
PAM and BLOSUM.

On Tue, Nov 10, 2009 at 1:52 AM, Satya Swarup Samal
<satya123...@gmail.com>wrote:

> Dear all,
>
> In sequence alignment algorithms e.g. Smith waterman or Needleman wunch, we
> have match, mismatch and gap score while comparing two sequences. But how we
> calculate these scores ? Is there any mathematical way or its just based on
> trial and error ?
>
> Thanx in advance
>
> --
> Best Regards
> Satya S. Samal
>
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Regards,

C. R. Hemalatha.

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