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biointelligence 31st dec
2009
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*Database f**or Protein Protein Interactions*
Proteins are organic compounds made of amino acids arranged in a linear
chain and folded into a globular form. These molecules are of great
importance because of the function they perform.
Protein associations are
studied from the perspectives of biochemistry, quantum chemistry, molecular
dynamics, signal transduction and other metabolic or genetic/epigenetic
networks. Protein-protein interactions are at the core of the entire
Interactomics system of any living cell. These interactions involve not only
the direct-contact association of protein molecules but also longer range
interactions through the electrolyte, aqueous solution medium surrounding
neighbor hydrated proteins over distances from less than one nanometer to
distances of several tens of nanometers. Furthermore, such protein-protein
interactions are thermodynamically linked functions of dynamically bound
ions and water that exchange rapidly with the surrounding solution by
comparison with the molecular tumbling rate (or correlation times) of the
interacting proteins.
The MIPS Mammalian
Protein-Protein Interaction Database is a collection of manually curated
high-quality Protein Protein Interaction data collected from the scientific
literature by expert curators. The content is based on published
experimental evidence that has been processed by human expert curators. MIPS
provide the full dataset for download and a flexible and powerful web
interface for users with various requirements.
Click here to access MIPS:
*http://mips.helmholtz-muenchen.de/proj/ppi/*
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*Regards,
Team Biointelligence
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*Biointelligence*
*Getting started with biosciences*
*Website: **www.biointelligence.in*
*Email: **i...@biointelligence.in**
Tel: +91-731-425-7930*
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