Christian Höner writes:
> no, but after skimming the paper it doesn't look that complicated to
> implement. There is also a bunch of related work on how to reduce the
> work involved in global MSA, i.e. on bounding the maximal deviation from
> the main diagonal...
> depends on what you want to actually do with the implementation.
What I am really looking for is making DNA-DNA alignments that take
reading frame/gene location into account - when comparing sequencing
data to expected sequence, after introducing mutations.
E.g. when 3 bases are deleted, the alignment would tend to remove an
entire codon, rather than 2 bases from one codon and 1 base from another
codon.
Best regards,
Adam
--
"Perl is a Shinto shrine." Adam Sjøgren
[email protected]