From: "Miao, Lingling (NIH/NIAMS) [F]" <[email protected]>
Reply-To: "Miao, Lingling (NIH/NIAMS) [F]" <[email protected]>
Date: Thursday, September 6, 2018 at 7:26 PM
To: List SINGLECELLGENOMICS-L <[email protected]>
Subject: Partek Single Cell RNA-Seq Data Analysis Seminar

Single Cell RNA-Seq Data Analysis Seminar

When: 1:00PM - 2:00PM, Wednesday, September 19th.
Where: Conference Room 1327, Building 50 (50/1327), NIH Campus

The Single Cell RNA-Seq data analysis pipeline in Partek Flow simplifies Single 
Cell RNA-Seq analysis, even for novices!  During this seminar session, Partek 
Scientist will show you how to analyze a Single Cell RNA-Seq data set with 
multiple biological replicates and detect genes that are differentially 
expressed between cell populations across sample groups in an intuitive, 
interactive and powerful way.

Agenda:
Partek Single Cell RNA-Seq Data Analysis Solution Overview
Live Demo

  *   Import count matrix text file or fastq files and upstream analysis 
pipeline on 10X prep kit if users are interested
  *   Filter cells using interactive QA/QC charts
  *   Filter low expressed genes
  *   Normalize raw count
  *   Visualize cell populations using the interactive 3D t-SNE plot
  *   Overlay gene expression and pathway signatures on the 3D t-SNE plot
  *   Select and classify cells on the 3D t-SNE plot
  *   Detect differentially expressed genes between sub populations
  *   Filter a gene list
  *   Identify enriched KEGG pathway and/or GO terms
  *   Visualize cell-level results using heat maps, volcano plots, and violin 
plots
Q&A



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