FYI….
Sean
Subject: NCBI CBB Seminar on Thursday, November 1, 2018 at 15:00
A seminar that may be of broad interest to the bioinformatics/data science
community
Speaker: Jessica Severin from RIKEN Yokohama Institute, IMS
Location: Building 38B2 NCBI Library (B2N14)
Host: Max Burroughs
Visualization and Analysis of Cell and Tissue Omics data with ZENBU genome
browser system
Recent genome-wide compendium studies, such as FANTOM5, Encode, Epigenome
Roadmap, TCGA, and more recently single-cell studies are changing the nature of
biological science due to their unprecedented breadth and scale. With this new
mode of research requires novel tools to visualize, analyze, and manage such
data.
To address this need, we developed the ZENBU system (Severin et al.,
/Nature Biotechnology/, 2014). ZENBU extends the genome browser concept by
integrating advanced, on-demand data processing and analysis with visualization
optimized for the comparison across 1000s of experimental samples. A key
feature of ZENBU is the data security and collaboration system, allowing users
to upload 100s-1000s of experimental data sets and share them with a selected
group of collaborators. ZENBU thus enables anyone from individual researchers
to large consortia to use the system with their unpublished data while
maintaining confidentiality.
ZENBU can easily work with both transcriptomics and epigenomics data sets
providing raw data visualization, data clustering, gene expression analysis and
comparative analysis as some examples. Recently, we have expanded ZENBU's
statistical toolbox to enable sample enrichment and grouping analysis.
Current areas of development include expanding the statistical analysis
capabilities and a new report-page visualization elements system.
ZENBU is the primary visualization system for the FANTOM consortium since
2010 with over 3million page hits per year and over 900 registered users.
