Ribomed's innovative technology has been recognized by the leading 
market research firm, Frost & Sullivan, with its award to Ribomed of 
the Biological Detection Technologies Excellence in Research of the 
Year Award for 2005. 

Ribomed Recognized by Frost & Sullivan for Excellence in Biological 
Detection Technologies Research

Naples, Fla. — May 25, 2005 — Frost & Sullivan will present Ribomed 
Biotechnologies, Inc. with
the 2005 Biological Detection Technologies Excellence in Research of 
the Year Award at
tonight's Excellence in Industrial Technologies Banquet.
Ribomed receives the Award for its excellence in research and 
development (R&D) and for its
introduction of the Abscription® process that detects both disease 
cells and germs that serve as
biological warfare agents.
Abscription, a contraction of abortive transcription, is a rapid, 
robust, isothermal, polymerase
chain reaction (PCR)-free method for detecting and quantifying 
target proteins and nucleic acids.
It is an integral part of Ribomed's RiboMaker® Detection System.
Abscription's development was driven by four major requirements in 
clinical, and later, biological
defense detection systems. The first was the inadequacy of 
conventional detection systems in
terms of time, efficiency, and practicality. The second was the 
rising cost of healthcare, which
created a need to improve diagnosis and drug development.
The third factor was the U.S. Government's apprehension about 
national security from biological
attacks both at home and abroad. Lastly, the growth of molecular 
genetics promotes molecular
detection of diseases and the development of disease- and patient-
specific drugs.
"Abscription uses the reiterative synthesis of short RNA Abscripts®, 
which are produced by the
RiboMaker® Abscriptase® enzyme, to rapidly generate thousands of 
detectable and quantifiable
signals per target per minute," says Frost & Sullivan research 
analyst Michael Valenti.
"Abscripts® are generated from an artificially created start site 
for Abscription, called an
Abscriptase ® Promoter Cassette (APC)."
Modular RiboMaker® APCs can be linked to targeted molecules such as 
RNA, DNA, or protein,
and, since Abscription is linear, the amount of Abscripts® generated 
is directly proportional to the
number of target molecules present.
Abscripts® can be tagged with reporters, affinity tags, or haptens 
during the Abscription process
by incorporating Ribomed's proprietary tagged Ribonucleotide analogs 
(RiboLogs®). They are
then fed into several different secondary signaling systems, leading 
to the rapid production of
millions of signals per target. Moreover, Abscription is highly 
conducive to multiplexing, and can
create more than 20 APCs, each producing a unique product.
By being able to identify infectious agents accurately in real time 
using the Abscription-based
RiboMaker detection tests, physicians can treat patients at their 
point-of-care, saving 72 hours of
culturing to pick an appropriate treatment.
"This time saving can be critical in determining whether persons are 
victims of a biological attack
and in devising the most appropriate method of treating them," notes 
Valenti. "It has also sparked
the funding by several agencies of the federal government in 
bioterrorism applications."
The National Institutes of Health (NIH/NCI, NIAID), the U.S. 
Department of Defense (DARPA),
and the Department of Homeland Security (HSARPA) have supported the 
development of
Abscription.
"Ribomed continues to exploit the robustness of the Abscription® 
process by developing a bloodbased
test for rapid development of vaccines to deadly viruses and 
bacteria," observes Valenti.
7550 IH 10 West, Suite 400
San Antonio, TX 78229
Tel. 210.348.1000 Fax 210.348.1003
www.frost.com
"The company has a novel approach to identifying both airborne and 
blood-transmitted pathogens
and early disease biomarkers, and has proved its superiority in R&D 
with its revolutionary
technologies for biological detection."
Frost & Sullivan presents its Excellence in Research of the Year 
Award to the company that has
carried out new, disruptive research in its industry. The Award 
recognizes a company's R&D
program that Frost & Sullivan expects will bring significant 
contributions to the industry in terms of
adoption, change, and competitive posture. The results of this 
research may already have altered
or will potentially impact certain market sectors.
Held in Naples, Fla., the Frost & Sullivan Excellence in Industrial 
Technologies Awards Banquet
honors world-class companies for outstanding performance and 
achievements in their industries.
An annual event, the banquet recognizes the quality and merit of 
distinguished individuals and
companies.
About Ribomed Biotechnologies, Inc.
Ribomed Biotechnologies, Inc. is a molecular diagnostics company 
developing rapid, specific and
robust tests for the early detection and characterization of 
diseases and their causative agents,
and the screening of drugs for treatment. Ribomed is dedicated to 
improving the quality of life
through early disease detection, noninvasive monitoring and patient-
specific therapies.
About Frost & Sullivan
Frost & Sullivan, a global growth consulting company, has been 
partnering with clients to support
the development of innovative strategies for more than 40 years. The 
company's industry
expertise integrates growth consulting, growth partnership services 
and corporate management
training to identify and develop opportunities. Frost & Sullivan 
serves an extensive clientele that
includes Global 1000 companies, emerging companies, and the 
investment community, by
providing comprehensive industry coverage that reflects a unique 
global perspective and
combines ongoing analysis of markets, technologies, econometrics, 
and demographics. For
more information, visit www.frost.com.
Contact:
Stacie Jones
210.247.2450
Stacie.jones @ frost.com

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