Berna Biotech Announces Two New Collaborations


· with the Australian-based biopharmaceutical company CSL regarding 
Aerugen for Australia and New Zealand 


 
· with the Swiss-based biopharmaceutical company Apoxis regarding 
recombinant protein production


BERNE, Switzerland, June 22, 2005--Berna Biotech Ltd (SWX: BBIN) 
announced today two new collaborations:

With CSL an exclusive commercialisation and licence agreement for 
AerugenÒ in Australia and New Zealand was signed. AerugenÒ is a 
vaccine for the prophylaxis of Pseudomonas aeruginosa infections in 
cystic fibrosis patients and is expected to be launched in Europe in 
the year 2007.

CSL Limited is a global, specialty biopharmaceutical company that 
develops, manufactures and markets products to treat and prevent 
serious human medical conditions; Headquartered in Melbourne 
Australia, the CSL Group includes CSL Bioplasma, CSL Pharmaceutical 
and ZLB Behring incorporating ZLB Plasma Services.

With Apoxis an agreement for clinical-grade, recombinant protein 
production and supply was signed: Berna will apply its mammalian-
cell process development expertise and state-of-the-art 
manufacturing facility to the production of Apoxis' recombinant 
MegaFasL product for phase I clinical trials in oncology.

Apoxis SA is a Swiss-based biopharmaceutical company. Apoxis 
develops novel therapeutic proteins able to modulate apoptotic cell 
death (cell suicide). Apoptosis plays a central role in the 
regulation of cancer and autoimmune disease and its control, through 
agonistic or antagonistic molecules, holds great promise for the 
treatment of life-threatening diseases. For further information see 
http://www.apoxis.com

No financial details were disclosed.

For further information:

Berna Biotech Ltd
Patrik Richard
Corporate Secretary
[EMAIL PROTECTED]
Phone +41 (0) 31 980 64 91
www.bernabiotech.com

CSL Ltd
Dr Rachel David
Director, Public Affairs
[EMAIL PROTECTED]
Phone 0401 775 779
www.csl.com.au

Apoxis SA
Cedric Haenni
Chief Operation Officer
[EMAIL PROTECTED]
Phone: +41 (0)21 620 60 82
www.apoxis.com


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