This is a MacBook Air running OS X 10.7.3. I have macports (http://www.macports.org) installed.
Here's what I did: $ sudo port install libunistring pkgconfig boehmgc gmp $ git clone git://git.sv.gnu.org/guile.git $ cd guile/ $ git checkout stable-2.0 $ ./configure -C --with-libgmp-prefix=/opt/local --with-libunistring-prefix=/opt/local $ make After about 450 lines of output, it fails with GEN guile-procedures.texi guile: uncaught throw to unbound-variable: (#f Unbound variable: ~S (mod) #f) I'd be happy to provide more details on request. Thanks!