After a Guix System reconfigure and upgrading packages, Scribus 1.5.5 and Pencil2D 0.6.4 work alright now (these are Qt-based applications). However, the problem persists in the GIMP 2.10.14.
$ LANG=C guix describe Generation 7 Jan 08 2020 13:53:10 (current) guix f98c050 repository URL: https://git.savannah.gnu.org/git/guix.git branch: master commit: f98c050c2017be06cff54abf965a8234f6998f76 I don't know what fixed the issue for Qt-based applications. --- https://sirgazil.bitbucket.io/