As reported by Mathieu in <https://issues.guix.gnu.org/41350>:
--8<---------------cut here---------------start------------->8--- $ cat ~/src/guix-debugging/graft-cross-compilation.scm (use-modules (gnu) (guix) (gnu packages gtk)) (with-store store (run-with-store store (mlet* %store-monad ((target (set-current-target "aarch64-linux-gnu")) (drv (lower-object (computed-file "test" #~(begin (mkdir #$output) #+guile-rsvg))))) (return (derivation->output-path drv))))) $ ./pre-inst-env guile ~/src/guix-debugging/graft-cross-compilation.scm Backtrace: In guix/gexp.scm: 243:18 19 (_ _) 1061:2 18 (_ _) 921:2 17 (_ _) 782:4 16 (_ _) In guix/store.scm: 1899:12 15 (_ #<store-connection 256.99 7ff08bb752d0>) 1336:2 14 (map/accumulate-builds #<store-connection 256.99 7ff08bb752d0> _ _) In srfi/srfi-1.scm: 586:17 13 (map1 ((#<package guile-rsvg@2.18.1-0.05c6a2f gnu/packages/gtk.scm:941 7ff080bf2f00> "out"))) In guix/store.scm: 1295:8 12 (call-with-build-handler #<procedure build-accumulator (continue store things mode)> _) 2017:24 11 (run-with-store #<store-connection 256.99 7ff08bb752d0> _ #:guile-for-build _ #:system _ #:target _) In guix/gexp.scm: 785:13 10 (_ _) In guix/store.scm: 1851:8 9 (_ _) In guix/gexp.scm: 243:18 8 (_ _) In guix/store.scm: 1886:38 7 (_ #<store-connection 256.99 7ff08bb752d0>) In guix/packages.scm: 1072:16 6 (package-derivation _ #<package guile-rsvg@2.18.1-0.05c6a2f gnu/packages/gtk.scm:941 7ff080bf2f00> _ #:graft? _) 1393:16 5 (thunk) 1280:6 4 (bag-grafts #<store-connection 256.99 7ff08bb752d0> #<<bag> name: "guile-rsvg-2.18.1-0.05c6a2f" system: "x86_64-linux" target: #f build-inputs: (("source" #<origin "https://gitlab.com…>) 1260:45 3 (fold-bag-dependencies #<procedure 7ff0867da880 at guix/packages.scm:1280:29 (package grafts)> _ _ #:native? _) 1072:16 2 (package->bag _ _ _ #:graft? _) 1183:21 1 (thunk) In ice-9/boot-9.scm: 1669:16 0 (raise-exception _ #:continuable? _) ice-9/boot-9.scm:1669:16: In procedure raise-exception: ERROR: 1. &package-cross-build-system-error: #<package gobject-introspection@1.62.0 gnu/packages/glib.scm:416 7ff0839365a0> --8<---------------cut here---------------end--------------->8--- This is on 4960a955f8f77cc4c35d0db749cd6f3de8787bff-ish. Ludo’.