I'm closing this issue because the package the report was filed against was removed from Guix:
gnu: jami-client-gnome: Remove deprecated package. commit 8551bc64e4322080ef07b5009f4d46229df8d6f3 Date: Sun Jul 12 18:00:46 2020 +0200 Also, there is a new package for Jami that I tried out: Guix System 97e98e2 Jami 20200710.1.6bd18d2 I followed the steps below to try reproduce the issue with this new version and I could not see any memory leak. 1. $ guix install jami 2. Press Alt+F2 and run "jami" 2.1. Create a Jami account 3. Press Alt+F2 and run "gnome-system-monitor" 4. Click on "Processes" 5. Locate the "jami" process 6. Observe the "Memory" use for a few hours Problem solved.