Starting from commit 53b9c27aa59bebf955f0aa24fef60a101480ef5c (a fix for <https://issues.guix.gnu.org/55987>), we get:
--8<---------------cut here---------------start------------->8--- $ ./pre-inst-env guix refresh -t cran r-a3 r-googlesheets r-a4 -u gnu/packages/bioconductor.scm:9233:2: warning: no updater for r-a4 guix refresh: warning: failed to retrieve package information from https://cran.r-project.org/web/packages/googlesheets/DESCRIPTION: 404 (Not Found) guix refresh: error: updater failed to determine available releases for r-googlesheets --8<---------------cut here---------------end--------------->8--- That is, ‘guix refresh -u’ stops on the first failure (in this case ‘r-a3’ is not processed). That makes it hard to use for mass updates as in ‘guix refresh -t cran -u’. (Reported by Ricardo on #guix.) Ludo’.