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Posted on behalf of Wolfram Saenger; please send enquiries/applications
to him directly:

A doctoral position is available in the group of  Prof. Wolfram Saenger,
Institute of Crystallography at Free University Berlin,

The group.
The succesful candidate is expected to work in the field of protein 
crystallography  on photosystem II.  We are a group of about 20 
postdocs. Ph.D. and diploma students and  technicians. We are well 
equipped for studies in biochemistry, molecular biology, protein X-ray 
crystallography and have vast experience in structural studies of 
photosystems I and II, protein-nucleic acid complexes, toxin-antitoxin 
systems and various enzymes.

The problem.
Photosynthesis is initiated at two large, membrane-embedded 
protein-cofacto r complexes, the photosystems I and II (PSI and PSII), 
where sun light initiates charge separation. We have determined the 
structures of PSI at 2.5 A resolution and of PSII at 3.8 A and now at 
3.0 A resolution. We are looking for a young scientist to help in 
structure determination of PSII at the
highest possible resolution to learn more about the still poorly 
understood function of the PSII complex that is of crucial importance in 
photosynthesis.

Methods.
X-ray crystallography at synchrotrons BESSY/Berlin, ESRF/Grenoble or 
SLS/Villigen. We also expect from the successful candidate to have an 
interest in protein purification and to have experience in basic 
biochemical methods.

Selected publications:
P. Jordan et al., Three dimensional structure of cyanobacterial 
photosystem I at 2.5 ? resolution. Nature 411, (2001 909-917.

A. Zouni et al.,Crystal structure of photosystem II from Synechococcus 
elon gatus at 3.8 ? resolution. Nature 409, (2001)739-743.

B. Loll et al., Towards complete cofactor assembly in photosystem II at 
3.0 A resolution. See  Nature 15. December 2005 issue.

Requirements.
It is of advantage but not a necessary requirement that the candidate 
has experience in crystallographic methods. The Ph.D. student will be 
supervised by a postdoc who is familiar with structure determination of 
PSII since nearly 4 years. It is required, however, that the candidate 
be fluent in English, can work independently after having been 
instructed, is very motivated and has a good scientific appetite.

Job conditions
The position is open from 1. Jan. 2006 for 4 years, the salary is 60% of 
BAT IIa (BAT IIa is the normal salary for a postdoc in Germany). The 
time to finish the Ph.D. dissertation is usually shorter than 4 years, 
the shorter the better, and can then be upgraded to full BAT IIa, 
depending onthe financial situation at that time. The position is in the 
frame of DFG-funded Sonderforschungsbereich (SFB) 498 (Collaborative 
Research Centre 498) with title "Protein-Cofactor Interactions". This is 
an interdisciplinary network with 22 different groups working on 
different projects in different research institutions in Berlin.

Addresses.
Prof. Dr. Wolfram Saenger
Institut fuer Kristallographie
Freie Universitaet Berlin
Takustr.6
14195 Berlin
Germany

phone (+49)-30-838-53412
fax (+49)-30-838-56702
e-mail [EMAIL PROTECTED]

Homepage: (SFB 498)                       
<http://www.physik.fu-berlin.de/sfb498/de/p-a4.htm>http://www.physik.fu-berlin.de/sfb498/de/p-a4.htm
  
(SFB 498) <http://www.physik.fu-berlin.de/sfb498/de/p-a4.htm>
                  (Group of W. Saenger)    
http://www.chemie.fu-berlin.de/ag/saenger/  
<http://www.physik.fu-berlin.de/sfb498/de/p-a4.htm>








        
        

        

        

        

        

        

        

        

        

        

        

        

        

        

        

        


-- 
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Prof. Dr. Wolfram Saenger
Institut fuer Kristallographie
Freie Universitaet Berlin
Takustr.6
14195 Berlin
Germany

phone (+49)-30-838-53412
fax (+49)-30-838-56702
e-mail [EMAIL PROTECTED]




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