Hi I'm going to need help understanding the chiral center table in Sketcher.
I'm going to need to figure out what "B/3", "F/4", "1/5" and "2/6" mean. Also, what cross0-6 mean and why sometimes this means there are only three atoms in the center and sometimes nine (are we talking larger rings here). Do I assume that R=+ and L=- or is there some other definition I should know about. "Both" seems like a nice option, but when it chooses the wrong one to regularize what do I do from there? I can even input a geometrically ~correct model (excepting some bond lengths and angles) and it switches the chiralities all ways round. I'm working on building precorrin-2. Containing 4 chiral centers, two each within five member rings and those rings within a tetrapyrrole. I can build Uro'gen III no problem (same basic structure just without the chiral centers). Boy wouldn't it be nice if the labels in Sketcher were just slightly offset from the white lines so I could actually tell C21 from C31 when there is a white line drawn in the middle and the label stays the same size even when I zoom to immense proportions. Thanks Heidi
